Anaphase-Promoting Complex-Cyclosome Apc7 Subunit
A highly conserved subunit of the anaphase-promoting complex (APC-C) containing multiple 34 amino acid tetratricopeptide repeats. These domains, also found in Apc3, Apc6, and Apc8, have been shown to mediate protein-protein interactions, suggesting that Apc7 may assist in coordinating the juxtaposition of the catalytic and substrate recognition module subunits relative to coactivators and APC-C inhibitors.
Also Known As:
Apc7 Subunit, Anaphase-Promoting Complex-Cyclosome; Anapc7; Apc7 Subunit, Anaphase-Promoting Complex; Apc7 Subunit, Anaphase Promoting Complex; Apc7 Subunit, Anaphase Promoting Complex Cyclosome
Networked: 6
relevant articles (0 outcomes,
1 trials/studies)
Bio-Agent Context: Research Results
Experts
| 1. | Bai, Ju:
1 article
(01/2022)
|
| 2. | Bronze, Michael S:
1 article
(01/2022)
|
| 3. | Chen, Hongli:
1 article
(01/2022)
|
| 4. | Feng, Yuandong:
1 article
(01/2022)
|
| 5. | Fung, Kar-Ming:
1 article
(01/2022)
|
| 6. | Gu, Lian:
1 article
(01/2022)
|
| 7. | He, Aili:
1 article
(01/2022)
|
| 8. | Houchen, Courtney W:
1 article
(01/2022)
|
| 9. | Huang, Xianli:
1 article
(01/2022)
|
| 10. | Jia, Yachun:
1 article
(01/2022)
|
Related Diseases
| 1. | Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
|
| 2. | Atherosclerosis
01/01/2022
- " Bioinformatics analysis revealed that the parental genes of differentially expressed circRNAs as well as the mRNAs predicted in the circRNA-miRNA-mRNA regulatory network are enriched for signaling pathways associated with IS pathology, such as the MAPK signaling pathway, lipid and atherosclerosis, neurotrophic factor signaling pathways, mTOR signaling pathway, the p53 signaling pathway etc. Then, 10 hub genes were identified from the PPI and module networks, including FBXW11, FBXW7, UBE2V2, ANAPC7, CDC27, UBC, CDC5L, POLR2H, POLR2F and RBX1. "
|
| 3. | Pancreatic Neoplasms (Pancreatic Cancer)
|
| 4. | Neoplasms (Cancer)
|
| 5. | Hepatocellular Carcinoma (Hepatoma)
|
|
Related Drugs and Biologics