Potassium Sparing Diuretics

04/10/2008 - "Non-potassium-sparing diuretics may increase mortality and hospitalizations in heart failure patients. "
06/01/2006 - "Non-potassium-sparing diuretics are commonly used in heart failure (HF). "
08/20/2003 - "We sought to determine whether non-potassium-sparing diuretics (PSDs) in the absence of a PSD may result in progressive heart failure (HF). "
08/01/1995 - "Potassium-sparing diuretics are usually reserved for neonates with congestive heart failure and are always used in combination."
08/01/2010 - "Non-potassium-sparing diuretics (NPSDs) still remain the cornerstone of therapy for fluid management in heart failure despite the lack of large randomized trials evaluating their safety and optimal dosing regimens in both the acute and chronic setting. "

11/14/2012 - "Blood pressure lowering efficacy of potassium-sparing diuretics (that block the epithelial sodium channel) for primary hypertension."
01/20/2010 - "Blood pressure lowering efficacy of potassium-sparing diuretics (that block the epithelial sodium channel) for primary hypertension."
01/01/2023 - "The aim of this study was to compare the BP-lowering efficacy and the incidence of adverse effects of high (T+) and low-dose (T-) thiazide diuretics, alone or combined with high (PS+) or low-dose (PS-) potassium-sparing diuretics in patients with primary hypertension. "
09/01/2011 - "•  Other potassium-sparing diuretics (amiloride or triamterene) are generally prescribed for essential hypertension as a fixed-dose combination with hydrochlorothiazide. "

10/01/2022 - "We computed performance characteristics for ascites-related ICD-10 codes (K70.31, K70.11, K71.51, R18.8), as well as loop and/or potassium-sparing diuretics. "
08/01/1976 - "Change in antikaliuretic response to potassium-sparing diuretics in patients with cirrhotic ascites."
01/01/1994 - "Although some clinical studies seem to prove the efficacy of nonantialdosteronic potassium-sparing diuretics in the treatment of ascites, no controlled study has compared the efficacy of these drugs with that of antialdosteronic diuretics. "
11/01/2009 - "Treatment of ascites consists of potassium sparing diuretics, loop diuretics, and/or paracentesis. "
08/01/1976 - "In 2 elderly patients with ascites due to hepatic cirrhosis, potassium excretion decreased during re-administration of potassium-sparing diuretics after recurrence of ascites following withdrawal of previous prolonged treatment. "

04/02/1997 - "Finally, potassium-sparing diuretics, especially spironolactone, play an important role in controlling high blood pressure in patients with primary aldosteronism. "
03/01/1994 - "Aldosteronism due to bilateral adrenal hyperplasia can be managed with sodium restriction and use of potassium-sparing diuretics."
01/01/1983 - "In these studies, it therefore appears that while potassium-sparing diuretics may remain the medical mainstay in treating primary aldosteronism, new converting enzyme inhibitors such as MK-421 may be more effective in treating secondary hyperaldosteronism, since potassium levels can be normalized without increasing aldosterone secretion."

11/01/2023 - "Our study suggested that controlling the protein targets of potassium-sparing diuretics and aldosterone antagonists may have beneficial results for osteoarthritis. "