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Change in antikaliuretic response to potassium-sparing diuretics in patients with cirrhotic ascites.

Abstract
In 2 elderly patients with ascites due to hepatic cirrhosis, potassium excretion decreased during re-administration of potassium-sparing diuretics after recurrence of ascites following withdrawal of previous prolonged treatment. An exaggerated antikaliuretic response and a paradoxic rise in potassium excretion are "unpredictable" changes which may occur during administration of potassium-sparing diuretics at different times in the same patient treated with the same drug.
AuthorsJ P Radó
JournalJournal of the American Geriatrics Society (J Am Geriatr Soc) Vol. 24 Issue 8 Pg. 340-3 (Aug 1976) ISSN: 0002-8614 [Print] United States
PMID939897 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Diuretics
  • Potassium
Topics
  • Aged
  • Ascites (drug therapy, etiology, urine)
  • Diuretics (therapeutic use)
  • Female
  • Humans
  • Liver Cirrhosis (complications, urine)
  • Male
  • Middle Aged
  • Potassium (administration & dosage, metabolism, urine)

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