Proton Therapy

01/01/2023 - "Safety and efficacy of stereotactic body proton therapy for high-risk lung tumors."
06/18/2021 - "Proton therapy has become a gold standard in the treatment of these neoplasms, as high dose escalation can be achieved regarding the target while maximizing the sparing of the healthy tissues near the tumor. "
01/01/2020 - "Proton beam therapy shows significant promise in addressing both short-term and long-term toxicities in both central nervous system (CNS) and non-CNS pediatric tumors."
10/01/2016 - "Proton therapy showed good outcome in ocular, nasal tumors, pediatric, skull-based and paraspinal tumors. "
10/01/2016 - "Notably, proton beam therapy is very useful for pediatric cancer; since the pediatric radiation dose to normal tissues should be reduced as much as possible because of the effect of radiation on growth, intellectual development, endocrine organ function and secondary cancer development. "

01/01/2019 - "In DRT for chordoma, proton therapy was associated with improved OS at 5 years in a multivariate analysis (100% vs 34.1%; P = .031), and a high dose for chordoma was significant for improved OS in a univariate analysis with both DRT (79.0% vs 54.1%; P = .027) and PRT (83.3% vs 77.4%; P = .007). "
06/01/2014 - "Chordoma management is more widely studied with en bloc resection and adjuvant proton-beam therapy demonstrating improved progression-free survival and overall survival. "
12/01/2022 - "Surgical resection is the gold standard treatment followed by adjuvant radiotherapy which includes photon therapy, proton beam therapy (PBT), gamma knife radiosurgery, etc. PBT has become an unparalleled therapeutic modality in the management of BS chordomas. "
12/04/2021 - "Therapeutic Efficacy of Variable Biological Effectiveness of Proton Therapy in U-CH2 and MUG-Chor1 Human Chordoma Cell Death."
12/01/2021 - "Our data indicate that pencil beam scanning proton therapy for sacral chordomas is both safe and effective. "

01/01/2023 - "Is an Endorectal Balloon Beneficial for Rectal Sparing after Spacer Implantation in Prostate Cancer Patients Treated with Hypofractionated Intensity-Modulated Proton Beam Therapy? "
12/01/2019 - "High efficacy of hypofractionated proton therapy with 4 fractions of 5 Gy as a boost to 50 Gy photon therapy for localized prostate cancer."
03/30/2015 - "This study has demonstrated the potential of using an improved beam angle arrangement to better exploit the theoretical dosimetric benefits of proton therapy and provided insights of selecting quality beam angles for localized prostate cancer treatment."
01/01/2021 - "Ultrahypofractionated proton beam radiation therapy for prostate cancer is effective with long-term bDFS comparable with other fractionation schedules and with minimal serious long-term GI and GU toxicity."
12/01/2019 - "Present data have demonstrated that proton beam therapy is safe and effective compared with the standard treatment options for prostate cancer. "

09/01/2018 - "A validated proton beam therapy patch-field protocol for effective treatment of large hepatocellular carcinoma."
10/01/2019 - "Stereotactic body radiation therapy (SBRT) and proton beam therapy (PBT) generally are safe and effective for non-operative hepatocellular carcinoma (HCC). "
12/01/2009 - "The authors have shown proton beam therapy to be both safe and effective for the treatment of patients with hepatocellular carcinoma. "
01/01/2019 - "This study documents the utilization and efficacy of proton beam therapy (PBT) in western patients with localized unresectable hepatocellular carcinoma (HCC). "
12/01/2017 - "This study aimed to evaluate the safety and efficacy of proton beam therapy for large hepatocellular carcinoma (HCC). "

12/01/2015 - "High-dose (66-75.6 Gy [RBE]) proton beam therapy without chemotherapy was an efficacious and safe treatment for older patients with esophageal cancer."
10/01/2021 - "Proton therapy of esophageal cancer is superior to photon radiation therapy in terms of normal tissue sparing. "
09/01/2010 - "The results suggest that proton-beam therapy is an effective treatment for patients with locally advanced esophageal cancer. "
01/01/2005 - "The results suggest that proton beam therapy is an effective treatment for patients with locally confined esophageal cancer. "
05/01/2023 - "Proton beam therapy could be a safe and effective treatment method for postoperative lymph node oligorecurrence of esophageal cancer. "