Polyphenols

08/09/2023 - "Several natural bioactive compounds, especially polyphenols, have been shown to be effective against cancer progression and do not exert toxic effects on healthy tissues. "
01/01/2021 - "A wide range of plant-derived polyphenol bioactive substances have been investigated in order to explore the anti-cancer effects of these natural compounds and to promote the effective treatment of cancer through apoptosis induction. "
01/01/2012 - "This review summarizes the main protective effects on the cardiovascular system and cancer resulting from moderate wine and beer intake due mainly to their common components, alcohol and polyphenols."
10/01/2010 - "The therapeutic efficacy of these polyphenols on tumor growth and the SphK1/S1P pathway were confirmed in animals using a heterotopic PC-3 tumor in place model. "
08/01/2010 - "Dietary polyphenols have been found to possess preventive and therapeutic potential against several types of cancers. "

11/01/2012 - "Polyphenol-rich foods, such as fruits and vegetables, are protective against cardiovascular diseases, but the mechanisms of the beneficial effects are still unknown. "
11/01/2008 - "The aim of this review is to discuss the accumulating evidence that suggests that grape extracts and purified grape polyphenols possess a diverse array of biological actions and may be beneficial in the prevention of some inflammatory-mediated diseases including cardiovascular disease. "
11/01/2022 - "It also highlights the improved physicochemical properties and possible molecular mechanisms of some major polyphenols administered as nanoformulations and describes the results of in vitro and in vivo studies performed in animal models of cardiovascular diseases (CVDs)."
06/08/2011 - "This study provides the possibility that polyphenols in passion fruit seeds are effective against cardiovascular diseases (CVDs)."
01/01/2007 - "Wine polyphenols are considered to be protective against cardiovascular diseases. "

07/17/2019 - "BP-Cs extract with the most abundant polyphenols was found to be the most effective in reducing inflammation by downregulating inflammatory-related genes expression and blocking the activation of MAPK and NF-κB signaling pathways. "
12/08/2018 - "Although polyphenol-rich foods have been shown to be beneficial for certain conditions; polyphenol-rich agraz fruit consumption did not impact inflammation and HDL function in the current study of women with MetS."
06/02/2021 - "An oily fish diet improved subclinical inflammation, while no significant effect was observed for dietary polyphenols."
01/01/2018 - "Together with results found in the literature, we can show that some polyphenols exert anti-fibrotic and myocardial protective effects by mediating inflammation, oxidative stress, and fibrotic molecular signals. "
11/01/2007 - "Understanding the regulatory steps and the multiple potential actions of polyphenols within the inflammatory cascade may help to define special polyphenols to be used for prevention and intervention in clinical conditions of inflammation. "

01/01/2023 - "These data require further research and will be beneficial in supporting polyphenol supplementation as a potential alternative treatment for regulating autophagy in neurodegenerative diseases."
01/01/2023 - "Our recent studies have strikingly indicated the presence of polyphenols in nutritional mushrooms and demonstrated their protective effects in different models of neurodegenerative disorders in humans and rats [5, 6]. "
11/11/2022 - "Moreover, plant-derived dietary polyphenols were also shown to exert protective effects against neurodegenerative diseases such as AD. "
01/01/2017 - "Several studies suggest that long term consumption of dietary polyphenols offers protection against development of neurodegenerative diseases. "
10/19/2007 - "Our data indicate that the inhibitory effects of polyphenols against 5-S-cysteinyl-dopamine formation are structure-dependent and shed further light on the mechanisms by which polyphenols exert protection against neuronal injury relevant to neurodegenerative diseases."

01/01/2017 - "Thus, whole common milk and PUFA-rich milk have shown to be beneficial in a normal metabolic condition, whereas common milk and milk enriched with PUFA and polyphenols improve metabolic effects of obesity."
11/01/2022 - "Overall, this study shows that anti-obesity and anti-inflammatory efficacy of cocoa is resilient to changes in polyphenol content and composition induced by fermentation or roasting. "
03/15/2023 - "Overall, dietary polyphenols show promise in the prevention and management of obesity for certain adults."
08/20/2017 - "Therefore, a global approach including integrated and networked omics techniques, virtual screening and epigenetic analysis is necessary to fully understand the molecular mechanisms of HS polyphenols and metabolites involved, as well as their possible implications in the design of safe and effective polyphenolic formulations for obesity."
08/01/2022 - "Protective effects of apple polyphenols on bone loss in mice with high fat diet-induced obesity."