A member of the tumor necrosis factor receptor superfamily found on most T-LYMPHOCYTES. Activation of the receptor by CD70 ANTIGEN results in the increased proliferation of CD4-POSITIVE T-LYMPHOCYTES and CD8-POSITIVE T-LYMPHOCYTES. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
Also Known As:
Tumor Necrosis Factor Receptor Superfamily, Member 7; Antigen, CD27; TNFRSF7 Receptor; Activation Antigen, T-Cell; Antigen, T-Cell Activation; CD27 Antigen; Receptor, TNFRSF7; T Cell Activation Antigen; Antigens, CD27; CD27 Antigens; T-Cell Activation Antigen