Conditions of abnormal THYROID HORMONES release in patients with apparently normal THYROID GLAND during severe systemic illness, physical TRAUMA, and psychiatric disturbances. It can be caused by the loss of endogenous hypothalamic input or by exogenous drug effects. The most common abnormality results in low T3 THYROID HORMONE with progressive decrease in THYROXINE; (T4) and TSH. Elevated T4 with normal T3 may be seen in diseases in which THYROXINE-BINDING GLOBULIN synthesis and release are increased.
Also Known As:
Euthyroid Sick Syndrome; Low T3 High T4 Syndrome; Low T3 and Low T4 Syndrome; Low T3-High T4 Syndrome; Low T3-Low T4 Syndrome; Non-Thyroidal Illness Syndrome; Sick Euthyroid Syndrome; High T4 Syndromes; Low T3 Low T4 Syndrome; Non Thyroidal Illness Syndrome; Syndrome, Non-Thyroidal Illness; Syndrome, Sick Euthyroid; Syndromes, Non-Thyroidal Illness; High T4 Syndrome; Low T3 Syndrome