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Emepronium
A muscarinic antagonist used mainly in the treatment of urinary syndromes. It is incompletely absorbed from the gastrointestinal tract and does not cross the blood-brain barrier.
Also Known As:
Cetiprin; Bromide, Emepronium; Emepronium Bromide; Benzenepropanaminium, N-ethyl-N,N,alpha-trimethyl-gamma-phenyl-
Networked:
30
relevant articles (
2
outcomes,
5
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amines: 4871
Quaternary Ammonium Compounds: 136
Emepronium: 30
Preparyl: 2
emepronium carrageenate: 1
Onium Compounds
Quaternary Ammonium Compounds: 136
Emepronium: 30
Preparyl: 2
emepronium carrageenate: 1
Related Diseases
1.
Urinary Incontinence
01/01/1981 - "
A double-blind controlled trial was conducted of emepronium bromide against placebo in elderly mentally ill patients in hospital with urinary incontinence.
"
01/01/1981 - "
A trial of emepronium bromide for the treatment of urinary incontinence in the elderly mentally ill.
"
06/01/1982 - "
The lack of effect of intramuscular emepronium bromide for urinary incontinence.
"
04/09/1977 - "
Emepronium bromide in urinary incontinence.
"
03/05/1977 - "
Response to oral and intramuscular emepronium bromide was assessed cystometrically in nine patients with urinary incontinence caused by an uninhibited bladder.
"
2.
Abnormal Reflex (Hyperreflexia)
04/01/1981 - "
The effect of 4 weeks' treatment with emepronium bromide in 20 incontinent female patients with detrusor hyperreflexia was compared to the effect in 20 patients who did not have uninhibited detrusor contractions during filling cystometry but who were unable to suppress a voluntarily induced detrusor contraction.
"
05/01/1983 - "
Emepronium bromide and flavoxate therapy of the idiopathic unstable bladder and neuropathic detrusor hyperreflexia showed improvement of the subjective symptoms, but not of the urodynamic findings.
"
05/01/1983 - "
In a urodynamic study, the effect of carbachol, distigmine and prostaglandin-F2 alpha on neuropathic detrusor areflexia and on the non-contracting detrusor as well as the effect of scopolamine, emepronium bromide and flavoxate on the idiopathic unstable bladder and neuropathic detrusor hyperreflexia were examined.
"
3.
Urge Urinary Incontinence (Urge Incontinence)
01/01/1986 - "
In the remaining 13 children, DI was found during more than half the cystometries performed, and 11 of these children, who also had urge incontinence, were treated with emepronium bromide, 400-600 mg daily (10-12 mg/kg) for 3 months.
"
01/28/1978 - "
Emepronium bromide and the treatment of urge incontinence.
"
01/01/1991 - "
In a prospective randomised study on treatment of females with motor urge incontinence, intravesically administered lidocaine-gel and oral emepronium bromide were compared using clinical and urodynamic parameters.
"
01/01/1989 - "
[Comparative study of the effectiveness of an intravesical administered lidocaine gel versus emepronium bromide in females with urge incontinence].
"
01/01/1987 - "
In a placebo-controlled, randomized, double-blind, cross-over study, terodiline (50 mg/d) was compared with emepronium (600 mg/d) in 20 patients with motor urge incontinence.
"
4.
Ulcer
03/02/1981 - "
[Esophageal ulcer caused by emepronium bromide].
"
06/23/1978 - "
Within a one-year period seven patients were observed who had developed ulcers of the upper and mid oesophagus after treatment with doxycycline hydrochloride (n = 3), emepronium bromide (n = 3) or Pantogar (n = 1).
"
5.
Spasm (Spasms)
01/01/1988 - "
The use of intravesically instilled Cetiprin is recommended only in cases of severe postoperative bladder spasms.
"
01/01/1988 - "
The effect of intravesically administered Cetiprin on bladder spasms after transurethral resection of the prostate.
"
01/01/1976 - "
In the Cetiprin group 9 patients had no vesical spasm postoperatively, whereas 1 had moderate and 1 had severe spasms.
"
01/01/1976 - "
To find out whether Cetiprin reduces the vesical spasms seen after cystotomias, a double-blind investigation including 22 men was carried out.
"
01/01/1988 - "
A double-blind study of the short-term effects of intravesically administered emepronium bromide (Cetiprin) versus placebo on bladder spasms after transurethral prostatectomy was done in 40 male patients.
"
Related Drugs and Biologics
1.
Flavoxate (Urispas)
2.
Lidocaine (Xylocaine)
3.
Suspensions
4.
Scopolamine (Hyoscine)
5.
Chlorides
6.
Carbachol (Carbastat)
7.
distigmine (distigmine bromide)
8.
Emepronium
9.
Doxycycline (Periostat)
10.
Cholinergic Antagonists (Anticholinergics)
Related Therapies and Procedures
1.
Therapeutics
2.
Transurethral Resection of Prostate (TURP)
3.
Intramuscular Injections
4.
Aftercare (After-Treatment)
5.
Intravesical Administration