Blepharitis

01/01/2021 - "Such eyedrops thus seem to be a safe and effective treatment for MGD-associated posterior blepharitis."
01/01/2023 - "The onset of anterior blepharitis after cataract surgery may be related to a gradual decrease in postoperative eye drops. "
01/01/2019 - "Past history of allergic reactions to other topical glaucoma medication was significantly correlated with the manifestation of blepharitis (Cox proportional hazard model, P<0.007) while age, sex, intraocular pressure reduction rate, number of administered eye drops, history of systemic allergic diseases were not. "
03/01/2001 - "In practice, dry eye can be associated with Sjögren's syndrome, allergies, infection, blepharitis, and preservative-containing eye drops."
11/01/2019 - "The use of AS eye drops was indicated for several diseases: corneal diseases (corneal ulcer or corneal persistent epithelial defects) (34.32%); Sjögren syndrome (17.16%); dry eye resulting from autoimmune disease (15.38%); and blepharitis/blepharospasm (12.43%). "

08/01/2010 - "Azithromycin provided significant improvement in signs and symptoms of blepharitis after 4 weeks of treatment compared with baseline and persisted in the 4-week follow-up period."
01/01/2018 - "Both topical azithromycin and oral azithromycin were found to be effective in improving the clinical signs and symptoms of posterior blepharitis. "
01/01/2011 - "ST provides a fast and effective treatment of acute blepharitis compared to azithromycin. "
05/01/2012 - "To assess the efficacy of topical 1.5% azithromycin in the treatment of moderate to severe chronic blepharitis and to compare the efficacy of two different treatment modalities. "
09/01/2008 - "Twenty-one patients diagnosed with posterior blepharitis were randomized in an open-label study to receive either azithromycin plus warm compresses (10 patients), or compresses alone (11 patients). "

03/19/2024 - "Lotilaner is effective in eradicating Demodex mites in individuals suffering from Demodex blepharitis according to RR for the intervention versus the control group of 3.55 (95% confidence interval [CI]: 2.87-4.40, P < .00001, I2 = 0%). "
01/01/2024 - "Our objective is to investigate Lotilaner as a potential treatment for Demodex blepharitis, assessing both the safety and efficacy of the ophthalmic formula in managing this disease. We conducted research in Web of Science, PubMed, Cochrane Library, and Scopus up to November 2023. "
03/19/2024 - "This review aims to assess the safety and efficacy of lotilaner in the treatment of Demodex blepharitis. "
06/01/2024 - "A comprehensive literature search was performed in the PubMed and Cochrane Library databases from inception until February 2024 to identify relevant trials investigating the use of lotilaner in patients with Demodex blepharitis. "
06/01/2024 - "Further research and long-term follow-up studies are warranted to assess the safety and effectiveness of lotilaner in treating Demodex blepharitis."

02/05/2024 - "Demodex blepharitis were treated with yellow oxid mercure ophthalmic ointment with a good outcome in 81,3%. "
04/01/1960 - "Selsunef ointment to treat squamous blepharitis."
04/01/2024 - "Treatment with ivermectin 1% topical ointment, once daily for 2 months, was effective in reducing the presence of collarettes and in improving symptoms in patients with Demodex blepharitis."
11/01/2017 - "This prospective, randomized, double-blind interventional case series was designed to evaluate the short-term efficacy of 0.03% tacrolimus ointment as a new therapeutic approach for refractory cases of posterior blepharitis. "
04/01/2024 - "To evaluate the efficacy of topical ivermectin 1% ointment, for the treatment of Demodex blepharitis. "

05/16/2012 - "Topical antibiotics were shown to provide some symptomatic relief and were effective in eradicating bacteria from the eyelid margin for anterior blepharitis. "
03/01/2015 - "The efficacy of these antibiotics has been believed to be their antiinflammatory and antibacterial actions, which suppress MGD-associated posterior blepharitis and growth of lid bacteria. "
01/01/2021 - "Further trials are needed to provide high quality evidence on the use of oral antibiotics in the treatment of chronic blepharitis."
10/13/2023 - "Herein, an antibacterial system based on antibiotic delivery was developed and applied in a blepharitis model induced by bacteria. "
10/13/2023 - "Antibiotic Delivery System for Treating Bacteria-Induced Anterior Blepharitis."

02/01/2006 - "Efficacy of topical cyclosporin 0.05% in the treatment of posterior blepharitis."
01/01/2008 - "Topical ciclosporin, however, has a much improved safety profile and is still used to treat a variety of ocular surface disorders including dry eye syndrome, vernal and atopic keratoconjunctivitis, severe blepharitis and high-risk corneal graft patients. "
02/01/2006 - "To investigate the efficacy of topical cyclosporine A 0.05% (tCsA) (Restasis, Allergan Pharmaceuticals) in the treatment of meibomian gland dysfunction (posterior blepharitis). "
11/01/2013 - "Eyes with PKAS had a significantly higher incidence of atopic blepharitis and preoperative corneal neovascularization, and therefore, we suggest systemic corticosteroids or cyclosporine to prevent PKAS in such high-risk cases."
05/01/2009 - "In these trials, cyclosporine 0.05% ophthalmic emulsion has shown efficacy for management of posterior blepharitis, ocular rosacea, post-LASIK dry eye, contact lens intolerance, atopic keratoconjunctivitis, graft-versus-host disease, and herpetic stromal keratitis. "

06/01/2022 - "A single or double application of ivermectin 1% cream is well tolerated and highly effective in reducing or eliminating the characteristic sleeves associated with Demodex blepharitis. "
04/01/2022 - "The purpose of this study was to evaluate the efficacy of topical ivermectin 1% cream application on the eyelashes in combination with eyelid hygiene in the treatment of Demodex blepharitis. "
04/01/2022 - "These findings support the efficacy of topical ivermectin 1% cream application in the treatment of Demodex blepharitis."
04/01/2022 - "Efficacy of Topical Ivermectin 1% in the Treatment of Demodex Blepharitis."
06/01/2011 - "The efficacy of oral ivermectin for the treatment of chronic blepharitis in patients tested positive for Demodex spp."

05/01/2021 - "The administration of terpinen-4-ol to the eyelid margins in a cyclic manner in Demodex blepharitis is effective against adult and hatching Demodex and breaks the vicious cycle."
01/01/2022 - "Randomized double-blind trial of wipes containing terpinen-4-ol and hyaluronate versus baby shampoo in seborrheic blepharitis patients."
04/01/2020 - "To evaluate terpinen-4-ol lid scrubs (Cliradex) with Microblepharoexfoliation (MBE) (BlephEx) in the treatment of Demodex blepharitis. "
04/01/2020 - "Double-Masked and Unmasked Prospective Study of Terpinen-4-ol Lid Scrubs With Microblepharoexfoliation for the Treatment of Demodex Blepharitis."
05/01/2021 - "Efficacy of cyclic therapy with terpinen-4-ol in Demodex blepharitis : Is treatment possible by considering Demodex's life cycle?"

10/01/2018 - "The objective of this study was to examine the efficacy of 7.5% tea tree oil (TTO) eyelash shampoo on the density of Demodex (Acari: Demodicidae) and ocular symptoms in patients with demodectic blepharitis. "
11/01/2021 - "The comparison of the efficacy of swabs containing tea tree oil and chamomile oil and baby shampoo (BS) in the treatment of seborrheic blepharitis was aimed. "
10/01/2018 - "Evaluation of the Efficacy of Tea Tree Oil On the Density of Demodex Mites (Acari: Demodicidae) and Ocular Symptoms In Patients With Demodectic Blepharitis."
01/01/2022 - "The purpose of our study is to see how beneficial is tea tree oil (TTO) for treating chronic blepharitis topically, with a focus on the Demodex mite. "
10/01/2021 - "The purpose of this study is to report a case of corneal epithelial defects resulting from topical treatment of blepharitis with tea tree oil (TTO). "

01/01/1994 - "Topical ciprofloxacin in the treatment of blepharitis and blepharoconjunctivitis."
10/01/1996 - "Topical ciprofloxacin is effective and well tolerated and is a useful treatment of bacterial conjunctivitis and blepharitis."
04/01/1995 - "In conclusion, topical ciprofloxacin was effective and well tolerated and would be a particularly useful agent for the treatment of bacterial conjunctivitis and blepharitis."
07/01/1996 - "A total of 131 patients, 65 treated with ciprofloxacin (42 with conjunctivitis and 23 with blepharitis) and 66 treated with norfloxacin (39 with conjunctivitis and 27 with blepharitis) were enrolled in the study at five centres in France. "
03/01/2003 - "The authors studied the epidemiology of external ocular infections and the therapeutic efficacy of topical ciprofloxacin and norfloxacin in the treatment of conjunctivitis and blepharitis. "

06/01/2024 - "Approval of this targeted therapy represents a significant milestone in ophthalmology and offers a promising treatment option for patients with Demodex blepharitis. "
01/01/2021 - "We aimed to evaluate the efficacy of periocular intense pulsed light (IPL) therapy in the treatment of moderate to severe acute blepharitis or blepharoconjunctivitis. "
03/01/2014 - "After 12 weeks of systemic therapy, severe complaints and blepharitis strongly improved and were seen in only 13.3% and 20% of the patients (P = 0.01). "
05/01/2013 - "Moist warm pads improve efficacy of background therapy in patients with meibomian gland hypofunction and have no effect in blepharitis with excessive meibomian gland secretion. "
06/01/2018 - "The aim of this study was to investigate the presence of Demodex infestation in chronic blepharitis cases that are resistant to therapy. "

01/01/2019 - "Seven to 10 days after treatment with microblepharon exfoliation, symptomatic wearers showed significant improvement in anterior blepharitis (mean difference, 0.60; P = .04), lid wiper staining (0.50; P = .06), and lid-parallel conjunctival folds (0.68, P = .02) along with orifice capping (median difference, 0.65; P < .001), foam (0.90; P < .001), secretion volume (0.69; P < .001), quality (0.74; P < .001), and expressibility (0.49; P = .002), which were also clinically significant changes. "
12/01/2019 - "Mean Demodex counts improved after treatment from 1.36 ± 1.233 to 0.48 ± 0.6 parasites per eyelash (P = 0.03), and the overall blepharitis symptoms score improved from 42.9 ± 22 to 32.7 ± 21 (P = 0.01). "
01/01/2020 - "After treatment of Demodex blepharitis, infestation was under control, followed by subjective improvement of ocular symptoms and a stable clinical outcome. "
01/01/2019 - "Demodex mites can play a role in the pathogenesis of blepharitis along with bacterial agents, especially in treatment-resistant cases or recurrent cases after treatment. "
11/01/2017 - "Patients were evaluated with a questionnaire and slit-lamp examination 14 days and 28 days after treatment, and symptoms and signs of blepharitis were compared to those observed at baseline. "

02/01/2013 - "In the present prospective, randomized and double blind trial the efficacy of two established treatment options for MGD and blepharitis was evaluated in symptomatic contact lens wearers. "
02/01/2013 - "In this prospective, randomized 2-centre trial 53 symptomatic contact lens wearers suffering from blepharitis were included. "
03/01/2024 - "Among contact lens wearers, 64.3% of the patients either were uncomfortable wearing contact lenses or experienced vision changes "sometimes" or "frequently." Demodex blepharitis results in a significant negative impact on daily activities, creating a psychosocial and symptomatic burden on patients."
07/01/2020 - "The putative ocular microbiome is consistent between right and left eyes and is affected by contact lens use (higher Pseudomonas levels) and blepharitis (higher Staphylococcus levels). "
03/01/2017 - "Contact lens wear and anterior blepharitis status were recorded, as well as symptoms and clinical features. "

01/01/2024 - "Laser Doppler flowmetry of the eyelid skin in combination with clinical, functional and instrumental research methods helped reveal with high sensitivity and specificity the eyelid damage in chronic mixed blepharitis. "
01/01/2024 - "[Laser Doppler flowmetry in the diagnosis of chronic mixed blepharitis]."
01/01/2018 - "to identify the role of laser scanning confocal microscopy (LSCM) in diagnostic and to assess the effectiveness of involutional blepharitis treatment. "
03/01/2021 - "Effect of 808-nm Laser Photobiomodulation Treatment in Blepharitis Rat Model."
03/01/2021 - "Laser PBM at 808 nm was effective in alleviating ocular signs and controlling inflammation in blepharitis rat model. "

01/01/2021 - "In parallel to the improvement in OSDI, LLT, and meibography, findings of acute blepharitis or blepharoconjunctivitis improved in slit-lamp examination. "
01/01/2022 - "The present study highlights the importance of screening patients for collarettes and Demodex blepharitis as part of every slit-lamp examination."
01/01/2024 - "Volunteers were prospectively recruited and classified by experienced doctors into suspected Demodex blepharitis or healthy controls using slit-lamp evaluation of the eyelid margin and an inquiry about symptoms. "
01/01/2022 - "In this retrospective study by 7 investigators at 6 eye care clinics, case records of consecutive patients who underwent a slit-lamp examination, regardless of chief complaint, were reviewed for Demodex blepharitis, as identified by the presence of collarettes. "
01/01/2020 - "Slit-lamp examination showed bilateral blepharitis. "