Asbestos

Asbestos. Fibrous incombustible mineral composed of magnesium and calcium silicates with or without other elements. It is relatively inert chemically and used in thermal insulation and fireproofing. Inhalation of dust causes asbestosis and later lung and gastrointestinal neoplasms.

Networked: 7103 relevant articles (76 outcomes, 935 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Carbone, Michele: 64 articles (11/2021 - 02/2002)
2.	Pass, Harvey I: 60 articles (11/2021 - 02/2002)
3.	Mirabelli, Dario: 57 articles (01/2022 - 04/2006)
4.	Mensi, Carolina: 52 articles (05/2022 - 07/2004)
5.	Magnani, Corrado: 52 articles (01/2022 - 01/2002)
6.	Marinaccio, Alessandro: 52 articles (01/2022 - 09/2002)
7.	Kishimoto, Takumi: 43 articles (10/2022 - 02/2002)
8.	Toyokuni, Shinya: 42 articles (11/2021 - 11/2008)
9.	Otsuki, Takemi: 39 articles (04/2021 - 10/2006)
10.	Mossman, Brooke T: 38 articles (01/2016 - 02/2002)

Related Diseases

1.	Neoplasms (Cancer) 11/15/2020 - "Detection of asbestos fibres in lung tissues is very useful, if not necessary, to complete the pathological dt9iagnosis of asbestos-related malignancies in the medicolegal field. " 03/01/2016 - "Furthermore, the mineralogical analysis by SEM-EDS (identification and quantification of inorganic fibers in general and asbestos in particular) of the fibers detected in the lung tissues is very useful, if not necessary, to complete the pathological diagnosis of asbestos-related malignancies in medicolegal field. " 01/01/2007 - "In addition there was a significant reduction of Asbestos and Hg from cancer cells, while markedly reduced normal cell telomere of lyg was increased to optimally high amounts of 500-530ng BDORTunits. " 06/01/1987 - "However, the work group does not believe that information was sufficient to assess the level of cancer risk associated with the ingestion and therefore, this potential hazard should not be discounted, and ingestion exposure to asbestos should be eliminated whenever possible." 12/02/2015 - "These results also indicated that asbestos exposure induced the reduction of anti-tumor immunity, and efforts to develop substances to reverse this reduction may be helpful in preventing the occurrence of asbestos-induced tumors. "
2.	Malignant Mesothelioma 02/23/2013 - "Malignant mesothelioma is an asbestos-related fatal disease with no effective cure. " 04/02/2010 - "Malignant mesothelioma is an asbestos-related fatal disease with no effective cure. " 01/01/2009 - "There is no effective cure or treatment for any of the lung or pleural asbestos related diseases; malignant mesothelioma has a median survival of just 6-12 months. " 08/01/1995 - "Most malignant mesothelioma cases are associated with pulmonary asbestos body (AB) counts significantly greater than those of the general population. " 05/20/1978 - "A study of the occupational histories of 52 females with malignant mesothelioma and certain of their relatives, carried out to measure the risk of this disorder attributable to indirect asbestos exposure, showed that a significantly greater number of husbands and fathers of cases than of controls worked in asbestos-related industries, and the relative risk for this factor was 10. "
3.	Mesothelioma 11/01/2020 - "Paediatric mesothelioma is exceptional and seems to be different from its adult counterpart with few asbestos exposures, more peritoneal primary, and a better outcome. " 01/01/2022 - "Exposure assessment was performed: (1) through experts' evaluation (considered as the gold standard for the purpose of this study), according to the guidelines of the Italian National Mesothelioma Registry (ReNaM) and (2) using a job-exposure matrix (SYN-JEM) to obtain qualitative (ever/never) and quantitative estimates of occupational asbestos exposure (cumulative exposure expressed in fibers per mL (f/mL)). " 08/15/2008 - "Some authors have suggested that the increase in mesothelioma rate with TSFE might be attenuated by clearance of asbestos from the lungs. " 01/01/2008 - "Mesothelioma mortality was based on cumulative exposure and time since first exposure, with the inclusion of a term for clearance of asbestos fibres from the lung. " 07/01/2007 - "However, some authors have suggested that the increase in mesothelioma rate with TSFE might be attenuated by clearance of asbestos from the lungs. "
4.	Lung Neoplasms (Lung Cancer) 01/01/2022 - "With regard to neighbourhood exposure, naturally occurring asbestos and women were both associated with a higher risk of lung cancer; however, such an increase was not significantly greater compared with that associated with other sources of asbestos exposure and men. " 06/01/2014 - "This study aimed to determine whether CT scan screening in asbestos-exposed workers is effective in detecting asymptomatic lung cancer using a systematic review and meta-analysis. " 12/01/2018 - "We previously showed that low-dose computed tomography (LDCT) screening in asbestos-exposed workers is effective in detecting lung cancer (LC) at an early stage. " 06/01/2014 - "CT scan screening in asbestos-exposed workers is effective in detecting asymptomatic lung cancer. " 01/01/1992 - ""Dose-response" dependence worked out by American scientists helped to reveal the linear dependence between carcinogenic risk factor, asbestos containing dust, and lung cancer formation, use it for basing the new MAC for asbestos containing dust taking into account the oncologic security."
5.	Asbestosis 03/01/2010 - "Asbestosis represents a significant respiratory problem despite the improvement in the workplace hygiene and a decrease in use of asbestos. " 06/01/1989 - "Significantly greater numbers of BAL neutrophils were also found in asbestos-exposed workers without asbestosis than in either smoking or nonsmoking control subjects. " 06/12/2009 - "The radiographic gold-standard for diagnosis of asbestosis has been the plain chest radiograph, and in many asbestosis-screening clinics, chest radiograph abnormalities in conjunction with a history of asbestos exposure have been the mainstay of diagnosis. " 01/01/2011 - "First, the narrow definition of asbestosis forged by medical experts in interwar Britain helped shape a public perception of the asbestos issue as finite and controllable. " 07/01/1985 - "Bronchoalveolar lavage and clearance of 99m-Tc-DTPA in asbestos workers without evidence of asbestosis."

Related Drugs and Biologics

1.	Carcinogens
2.	Serpentine Asbestos (Chrysotile)
3.	beta Carotene (Betacarotene)
4.	Vitamin A (Retinol)
5.	Biomarkers (Surrogate Marker)
6.	Silicon Dioxide (Silica)
7.	DNA (Deoxyribonucleic Acid)
8.	Benzene (Benzole)
9.	Mercury
10.	Amphibole Asbestos

Related Therapies and Procedures

1.	Therapeutics
2.	Drug Therapy (Chemotherapy)
3.	Gamma Cameras (Gamma Camera)
4.	Orchiectomy (Orchidectomy)
5.	Chemoprevention