Cefpodoxime Proxetil (Vantin)

A prodrug of its active metabolite CEFPODOXIME.

Also Known As:

Vantin; CS 807; CS-807; U 76252; 76252, U; 807, CS; 807, Cephalosporin; Proxetil, Cefpodoxime; U76252; 1-(Isopropoxycarbonyloxy)ethyl-7-(2-(2-Amino-4-thiazolyl)-2-(Methoxyimino)Acetamido)-3-Methoxymethyl-8-oxo-5-thia-1-Azabicyclo(4,2,0)-oct-2-ene-2-Carboxylate; Cephalosporin 807; Orelox; Otreon; U-76252

Networked: 100 relevant articles (15 outcomes, 32 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Shapiro, Adam B: 3 articles (01/2021 - 11/2020)
2.	Carter, Nicole M: 2 articles (01/2021 - 11/2020)
3.	Gao, Ning: 2 articles (01/2021 - 01/2021)
4.	Miller, Alita A: 2 articles (01/2021 - 11/2020)
5.	Perry, C M: 2 articles (01/2001 - 01/2001)
6.	Kumar, Anoop: 1 article (01/2022)
7.	Sharma, Pankaj Kumar: 1 article (01/2022)
8.	Shukla, Vikesh Kumar: 1 article (01/2022)
9.	Moussa, Samir H: 1 article (01/2021)
10.	Chen, April: 1 article (11/2020)

Related Diseases

1.	Pharyngitis (Sore Throat) 08/01/1997 - "Efficacy of 5-day cefpodoxime proxetil for recurrent pharyngitis in adults. " 04/01/1995 - "Pharyngitis/tonsillitis: European and United States experience with cefpodoxime proxetil." 09/01/1991 - "It is concluded that cefpodoxime proxetil is as effective and safe as penicillin V potassium in the treatment of pharyngitis due to S pyogenes." 04/01/1993 - "This multicenter, randomized, parallel treatment, observer-blinded study was designed to evaluate the safety and efficacy of cefpodoxime proxetil (5 mg/kg twice daily for 10 days) compared with penicillin V (13.4 mg/kg three times daily for 10 days) for treatment of Group A streptococcal pharyngitis and tonsillitis in pediatric patients. " 01/01/1994 - "Thus, the shorter duration of therapy, in conjunction with demonstrated clinical and bacteriological efficacy that is equivalent to standard therapy, makes cefpodoxime proxetil an acceptable alternative for the treatment of GABHS pharyngitis/tonsillitis."
2.	Infections 11/01/1995 - "A multi-institutional study on clinical effectiveness of cefpodoxime proxetil dry syrup in childhood infections." 01/01/1994 - "In this study, we evaluated the clinical efficacy of cefpodoxime proxetil (CPDX-PR) in otorhinolaryngological infections. " 02/01/1990 - "This study suggests that cefpodoxime proxetil taken once or twice daily will be sufficient to treat urinary or systemic infections caused by susceptible pathogens." 07/01/1989 - "[Study of efficacy, safety and dosage on cefpodoxime proxetil in pediatric infections]." 11/01/1995 - "Clinical evaluation of cefpodoxime proxetil in patients with dermatological infections."
3.	Pneumonia (Pneumonitis) 01/01/1991 - "In mice with experimental pneumonia, cefpodoxime proxetil caused sharp falls in K. " 08/01/1996 - "Cefpodoxime proxetil has proven efficacy in the treatment of community-acquired pneumonia and upper respiratory tract, skin and soft tissue and urinary tract infections. " 04/01/1995 - "The clinical usefulness of cefpodoxime proxetil (CPDX-PR) was investigated in the treatment of pneumonia and chronic airway infections occurring in patients first visiting our outpatient clinic or those being treated at the outpatient clinic. " 11/01/2002 - "Cefditoren pivoxil versus cefpodoxime proxetil for community-acquired pneumonia: results of a multicenter, prospective, randomized, double-blind study." 08/01/1996 - "Thus, evidence to date suggests that cefpodoxime proxetil has potential for use as stepdown therapy in community-acquired pneumonia and in abbreviated therapy courses in upper respiratory tract infections. "
4.	Sinusitis 12/01/1990 - "The efficacy and tolerance of cefpodoxime proxetil were compared with those of cefaclor in a multicentre, international, prospective, double-blind, placebo-controlled study in adult outpatients suffering from acute sinusitis. " 12/01/1990 - "Comparison of cefpodoxime proxetil with cefaclor in the treatment of sinusitis." 08/01/1996 - "Data from preliminary clinical studies suggest that a 5-day course of cefpodoxime proxetil is as effective as an 8-day course of amoxicillin/clavulanic acid in treating either acute otitis media or sinusitis, and as effective as a 10-day course of amoxicillin/ clavulanic acid and more effective than a 10-day course of phenoxymethyl- penicillin in the treatment of pharyngotonsillitis. " 12/01/1990 - "The efficacy of cefpodoxime proxetil has been studied in ten clinical trials conducted in adults suffering from lower respiratory tract infections (pneumonia, acute bronchitis or acute on chronic bronchitis) and upper respiratory tract infections (tonsillitis/pharyngitis or sinusitis). " 08/01/2012 - "A multicentric, open label, randomised, postmarketing efficacy study comparing multidose of lincomycin hydrochloride capsule 500 mg with multidose cefpodoxime proxetil tablet 200 mg in patients with tonsillitis, sinusitis."
5.	Urinary Tract Infections (Urinary Tract Infection) 10/01/1997 - "He was prescribed a 10-day course of cefpodoxime proxetil for a possible urinary tract infection. " 01/01/1991 - "Review of clinical experience in the United States with cefpodoxime proxetil in adults with uncomplicated urinary tract infections." 08/01/1988 - "[A clinical evaluation of CS-807 in patients with urinary tract infections]." 01/01/2021 - "The combination of ETX0282 with cefpodoxime proxetil is in clinical trials as an oral therapy for complicated urinary tract infections caused by Enterobacterales. " 08/01/1996 - "Cefpodoxime proxetil has proven efficacy in the treatment of community-acquired pneumonia and upper respiratory tract, skin and soft tissue and urinary tract infections. "

Related Drugs and Biologics

1.	Penicillin V (Phenoxymethylpenicillin)
2.	Cefaclor (Ceclor)
3.	Amoxicillin (Wymox)
4.	Cefixime (Suprax)
5.	Cefdinir (Omnicef)
6.	cefditoren pivoxil (Spectracef)
7.	CS 834
8.	cefteram pivoxil
9.	Cefpodoxime
10.	Clavulanic Acid (Potassium Clavulanate)

Related Therapies and Procedures

1.	Therapeutics
2.	Renal Dialysis (Hemodialysis)
3.	Anesthesia
4.	Oral Administration
5.	Duration of Therapy