Post-Infectious Disorders

Debilitating disorder characterized by fatigue and other symptoms related to cognitive, autonomous, and immune dysfunction experienced in the aftermath of infections.

Also Known As:

Post Infection Syndrome; Post Infectious Disease Syndrome; Post Infectious Disorder; Post-Infection Syndromes; Post-Infectious Disease Syndromes; Post-Infectious Disorder; Syndrome, Post-Infection; Syndrome, Post-Infectious Disease; Post Active Phase of Infection Syndrome; Post Infectious Disorders; Post-Infection Syndrome; Post-Infectious Disease Syndrome

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Signs and Symptoms Pathological Conditions
- Pathologic Processes: 10385
  - Disease Attributes: 18
    - Chronic Disease: 26704
      - Post-Infectious Disorders: 3
        Guillain-Barre Syndrome: 3789
        Reactive Arthritis: 1301
        Post-Acute COVID-19 Syndrome: 995
        Acute Disseminated Encephalomyelitis: 547
        Post-Lyme Disease Syndrome: 134

Related Diseases

1.	Cognitive Dysfunction
2.	Anhedonia
3.	Pain (Aches)
4.	Inflammation (Inflammations)
5.	Campylobacter Infections (Campylobacter Infection)

Experts

1.	Anthony, Daniel C: 1 article (01/2024)
2.	Dunstan, Isobel K: 1 article (01/2024)
3.	McLeod, Ross: 1 article (01/2024)
4.	Pate, Trinity: 1 article (01/2024)
5.	Probert, Fay: 1 article (01/2024)
6.	Radford-Smith, Daniel E: 1 article (01/2024)
7.	Xiong, Wenzheng: 1 article (01/2024)
8.	Ardid, Denis: 1 article (01/2022)
9.	Barnich, Nicolas: 1 article (01/2022)
10.	Baudu, Elodie: 1 article (01/2022)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Post-Infectious Disorders:

1.	Toll-Like Receptors (Toll-Like Receptor)IBA 01/01/2024 - "Post-infection syndromes are characterised by fatigue, muscle pain, anhedonia, and cognitive impairment; mechanistic studies exploring these syndromes have focussed on pathways downstream of Toll-like receptor (TLR) 4 activation. "
2.	CytokinesIBA 01/01/2024 - "The results highlight how the cytokine profile induced by one PAMP cannot be extrapolated to another, but they do reveal how the manipulation of the conserved metabolome response might afford a more generic approach to the treatment of post-infection syndromes."
3.	VaccinesIBA 01/01/2020 - "Our work emphasizes the potential of FliD as a target for the development of vaccines and supports the concept that orally administered FliD-reactive SIgA can be developed to prevent or mitigate the severity of Campylobacter infections as well as the development of post-infection syndromes."
4.	Secretory Immunoglobulin A (SIgA)IBA 01/01/2020 - "Our work emphasizes the potential of FliD as a target for the development of vaccines and supports the concept that orally administered FliD-reactive SIgA can be developed to prevent or mitigate the severity of Campylobacter infections as well as the development of post-infection syndromes."
5.	Volatile Fatty AcidsIBA 01/01/2022 - "These post-infectious disorders were associated with low-grade inflammation, increased intestinal permeability, decrease of Lactobacillaceae abundance associated with the colonic layer, and increase of short-chain fatty acids (SCFAs). "
6.	Pathogen-Associated Molecular Pattern MoleculesIBA 01/01/2024 - "The results highlight how the cytokine profile induced by one PAMP cannot be extrapolated to another, but they do reveal how the manipulation of the conserved metabolome response might afford a more generic approach to the treatment of post-infection syndromes."