Antiglycation Agents

Compounds that reduce the non-enzymatic glycation of proteins, lipids, and nucleic acids AND thus reducing the formation of ADVANCED GLYCATION END-PRODUCTS.

Also Known As:

Agent, Anti-Glycating; Agent, Anti-Glycation; Agent, Anti-Glycative; Agent, Antiglycating; Agent, Antiglycation; Agent, Antiglycative; Agents, Anti-Glycating; Agents, Anti-Glycation; Agents, Anti-Glycative; Agents, Antiglycating; Agents, Antiglycation; Agents, Antiglycative; Anti Advanced Glycation End Products Agents; Anti Glycation Agent; Anti-Advanced Glycation End-Products Agents; Anti-Glycant; Anti-Glycants; Anti-Glycating Agent; Anti-Glycating Agents; Anti-Glycation Agent; Anti-Glycation Agents; Anti-Glycative Agent; Anti-Glycative Agents; Antiglycant; Antiglycants; Antiglycating Agent; Antiglycating Agents; Antiglycation Agent; Antiglycative Agent; Antiglycative Agents

Networked: 31 relevant articles (2 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Chemical Actions and Uses
- Pharmacologic Actions: 160
  - Molecular Mechanisms of Pharmacological Action: 24
    - Antiglycation Agents: 31

Experts

1.	Adisakwattana, Sirichai: 4 articles (12/2016 - 05/2013)
2.	Gugliucci, A: 3 articles (12/2009 - 04/2003)
3.	Abbas, Ghulam: 2 articles (01/2016 - 02/2013)
4.	Thilavech, Thavaree: 2 articles (04/2015 - 04/2014)
5.	Garner, A Christopher: 1 article (10/2021)
6.	Hipkiss, Alan R: 1 article (10/2021)
7.	Sale, Craig: 1 article (10/2021)
8.	Turner, Mark D: 1 article (10/2021)
9.	Iacobini, Carla: 1 article (09/2021)
10.	Menini, Stefano: 1 article (09/2021)

Related Diseases

1.	Hyperglycemia 01/01/1993 - "Incubation with 0.005 mmol/l acetylsalicylic acid, an effective anti-glycation agent, was partially protective against hyperglycemia-induced growth retardation, neural tube defects as well as the deleterious effects on the morphological development of specific tissues. " 01/01/2016 - "Here, we report that delayed intervention with pyridoxamine (PM), a vitamin B6 analog that has been identified as an antiglycating agent, protected against high-fat diet (HFD)-induced body weight gain, hyperglycemia, and hypercholesterolemia, compared with mice that were not treated. "
2.	Neural Tube Defects (Exencephaly) 01/01/1993 - "Incubation with 0.005 mmol/l acetylsalicylic acid, an effective anti-glycation agent, was partially protective against hyperglycemia-induced growth retardation, neural tube defects as well as the deleterious effects on the morphological development of specific tissues. "
3.	Cataract (Cataracts) 01/01/2015 - "officinale also exhibits protective effects against several diabetes-linked complications, notably nephropathy and diabetic cataract, by acting as an antioxidant and antiglycating agent. "
4.	Diabetes Complications 05/01/2018 - "These findings suggest that MGE may serve as a new promising antiglycative agent against diabetic complications by inhibiting protein glycation and glycoxidation." 10/04/2016 - "The synergistic effect of antiglycating agents (MB-92) on inhibition of protein glycation, misfolding and diabetic complications in diabetic-atherosclerotic rat." 04/07/2014 - "This edible plant could be a natural rich source of antiglycation agent for preventing AGE-mediated diabetic complication." 02/27/2013 - "Similarly, antiglycation agents may have application for the management of late diabetic complications." 03/01/2012 - "Natural products as anti-glycation agents: possible therapeutic potential for diabetic complications."
5.	Diabetes Mellitus 01/07/2014 - "Extraction process optimization of polyphenols from Indian Citrus sinensis - as novel antiglycative agents in the management of diabetes mellitus." 09/01/2015 - "These studies suggest that certain triterpenes are potent anti-glycative agents, and may benefit the prevention and/or therapy of glycation-related diseases such as diabetes mellitus and Alzheimer's disease. "

Related Drugs and Biologics

1.	Antioxidants
2.	Aspirin (Acetylsalicylic Acid)
3.	Reactive Oxygen Species (Oxygen Radicals)
4.	Cytokines
5.	Triterpenes
6.	3,3',4,5'-tetrahydroxystilbene
7.	cyanidin
8.	Proteins (Proteins, Gene)
9.	Carnosine
10.	Polyphenols

Related Therapies and Procedures

1.	Therapeutics