Antimicrobial Peptides

Small peptides that play an important role in early innate and induced defenses against invading microbes. Most have positive overall charges and are referred to as cationic antimicrobial peptides.

Also Known As:

Networked: 3727 relevant articles (175 outcomes, 319 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Gallo, Richard L: 57 articles (01/2022 - 09/2002)
2.	Chen, Jyh-Yih: 44 articles (03/2021 - 03/2007)
3.	Harder, Jürgen: 20 articles (11/2021 - 07/2006)
4.	Pan, Chieh-Yu: 20 articles (01/2021 - 05/2010)
5.	Hancock, Robert E W: 18 articles (11/2022 - 07/2005)
6.	Wang, Lei: 17 articles (07/2022 - 07/2007)
7.	Agerberth, Birgitta: 17 articles (01/2021 - 06/2004)
8.	Park, Yoonkyung: 16 articles (08/2022 - 08/2004)
9.	Brandenburg, Klaus: 16 articles (03/2021 - 10/2007)
10.	Rivas-Santiago, Bruno: 16 articles (01/2021 - 01/2006)

Related Diseases

1.	Infections 08/26/2023 - "Due to their effectiveness and specificity, antimicrobial peptides (AMPs) hold excellent promise for treating various infections caused by pathogens. " 02/01/2015 - "Host defense (antimicrobial) peptides (HDPs) are produced by virtually all organisms and have an important role in protection against microbial infections. " 07/17/2008 - "The changes detected upon colonization suggest that Paneth cell antimicrobial peptides may play an important role in commensal microbial homeostasis, in addition to their proposed role in protection against infection. " 09/01/2014 - "Because antimicrobial peptides (AMPs) are potentially useful for the treatment of multidrug-resistant infections, more attention is being paid to the structural modification and structure-function relationship of both naturally occurring and synthetic AMPs. " 05/17/2022 - "Antimicrobial peptides (AMPs) are widely studied as therapeutic agents due to their broad-spectrum efficacy against infections. "
2.	Bacterial Infections (Bacterial Infection) 01/01/2020 - "Antimicrobial peptides (AMPs) are an important part of the human innate immune system for protection against bacterial infections, however the AMPs display varying degrees of activity against Staphylococcus aureus. " 11/01/2020 - "Design of a Sea Snake Antimicrobial Peptide Derivative with Therapeutic Potential against Drug-Resistant Bacterial Infection." 01/01/2015 - "Protective effects of human milk antimicrobial peptides against bacterial infection." 11/01/1999 - "The goal of this study was to investigate whether the overexpression of an antimicrobial peptide results in augmented protection against bacterial infection. " 06/07/2020 - "Antimicrobial peptides (AMPs) show promise for the treatment of bacterial infections, but many have undesired hemolytic activities. "
3.	Wounds and Injuries (Trauma) 01/01/2008 - "Finally, by in vivo adenoviral transfer of the antimicrobial peptide to excisional wounds in ob/ob mice, we demonstrated that LL-37 significantly improved re-epithelialization and granulation tissue formation. " 05/19/2020 - "The focus should be put on the discovery of new drugs or the combination of existing drugs for a better synergy, taking into account all kinds of wounds and existing pathogens, and more specifically on the development of next-generation antimicrobial peptides, encompassing the delivery carrier toward improved pharmacokinetics and efficacy." 11/01/2019 - "Antimicrobial peptides can have a dual role with both antimicrobial activity against a broad range of bacteria and immunomodulatory effect, making them attractive as therapeutic treatment of difficult wounds. " 01/01/2023 - "Herein, this study describes a near-infrared (NIR) light-responsive microneedle patch for on-demand release of antimicrobial peptide for treatment of wound biofilms. " 01/01/2023 - "In this study, an antimicrobial wound dressing is prepared using a novel antimicrobial peptide, HX-12C. "
4.	Communicable Diseases (Infectious Diseases) 01/01/2018 - "Antimicrobial peptides (AMPs) have emerged as a new therapeutic class with great potential against infectious diseases, as they are less prone to induce resistance. " 12/01/2014 - "Antimicrobial peptides (AMPs) have therapeutic potential against infectious diseases and have the ability to target microbial pathogens within eukaryotic cells. " 08/01/2013 - "Our results suggest that during healthy aging the maintenance of the antimicrobial peptide innate immune response may be responsible for the protection against infectious diseases. " 01/01/2006 - "Currently, several studies are exploring the possibility of using these antimicrobial peptides as new therapeutic agents against different infectious diseases." 09/07/2023 - "Connatural antimicrobial peptide (AMPs) of female reproductive tract (FRT) conjunctly with these beneficial microbes provide protection from a large number of infectious diseases. "
5.	Inflammation (Inflammations) 05/01/1999 - "The purpose of this study was to investigate the presence of an antimicrobial peptide, human defensin-1, in the saliva of patients with oral inflammation. " 08/01/2023 - "Antimicrobial peptides (AMPs) are active molecules in the human innate immune system, that participate in host defense and regulate the inflammation process. " 04/30/2023 - "Recombinant Antimicrobial Peptide OaBac5mini Alleviates Inflammation in Pullorum Disease Chicks by Modulating TLR4/MyD88/NF-κB Pathway." 01/01/2023 - "During inflammation, the skin deploys antimicrobial peptides (AMPs) yet during allergic inflammation it becomes more susceptible to Staphylococcus aureus. " 01/01/2023 - "Competition between skin antimicrobial peptides and commensal bacteria in type 2 inflammation enables survival of S. "

Related Drugs and Biologics

1.	Anti-Bacterial Agents (Antibiotics)
2.	Cathelicidins
3.	Peptides (Polypeptides)
4.	Adenosine Monophosphate (AMP)
5.	Proline (L-Proline)
6.	Vitamin D
7.	Messenger RNA (mRNA)
8.	Defensins
9.	Chemokines
10.	Cecropins

Related Therapies and Procedures

1.	Therapeutics
2.	Drug Therapy (Chemotherapy)
3.	Photochemotherapy (Photodynamic Therapy)
4.	Phage Therapy
5.	Immunotherapy