Eucalyptol

A monoterpene and cyclohexanol derivative that is the major component of EUCALYPTUS OIL. It is used in mouthwash, insect repellent, and as a cough suppressant, and also is widely used as a flavoring agent and solvent. It has antimicrobial properties.

Also Known As:

Networked: 197 relevant articles (36 outcomes, 51 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Dethlefsen, Uwe: 5 articles (11/2013 - 04/2004)
2.	Leal-Cardoso, José Henrique: 4 articles (01/2022 - 12/2002)
3.	Kaltschmidt, Barbara: 4 articles (01/2019 - 12/2013)
4.	Kaltschmidt, Christian: 4 articles (01/2019 - 12/2013)
5.	Sudhoff, Holger: 4 articles (01/2019 - 12/2013)
6.	Seol, Geun Hee: 4 articles (01/2016 - 05/2014)
7.	Wei, Chengxi: 3 articles (06/2022 - 10/2021)
8.	Widera, Darius: 3 articles (10/2021 - 12/2013)
9.	Li, Qing: 3 articles (06/2021 - 12/2018)
10.	Bhattacharjee, Paramita: 3 articles (01/2021 - 01/2019)

Related Diseases

1.	Rhinosinusitis 01/01/2023 - "For acute post-viral rhinosinusitis, Cineole and Pelargonium sidoides were the most effective treatments for controlling symptoms (moderate certainty), while Spicae aetheroleum was most effective for health-related quality of life (HRQoL) improvement (moderate certainty). " 04/01/2004 - "Nonpurulent rhinosinusitis can be treated successfully with cineole. " 06/19/2023 - "Cineole can be considered as a safe and well-tolerated rhinosinusitis treatment conferring a clear improvement in quality of life outcomes." 01/01/2015 - " the present study, we successfully established ex vivo cultures of human nasal turbinate slices to investigate the effects of 1,8-cineol on mucus hypersecretion in experimentally induced rhinosinusitis. " 06/19/2023 - "Significant improvements in frequency (64.0%), bothersomeness (52.1%), and impact (53.9%) of rhinosinusitis symptoms were reported upon treatment with cineole over a mean treatment period of seven days (p < 0.001 each). "
2.	Asthma (Bronchial Asthma) 03/01/2003 - "Anti-inflammatory activity of 1.8-cineol (eucalyptol) in bronchial asthma: a double-blind placebo-controlled trial." 10/01/2012 - "Patients with asthma benefit from concomitant therapy with cineole: a placebo-controlled, double-blind trial." 10/01/2012 - "Based on these pharmacodynamic effects, we arrived at the hypothesis that asthma patients would benefit from concomitant therapy with cineole. " 02/10/2021 - "Particularly, the bioactive compounds, siphonochilone and eucalyptol, found in the roots and rhizomes have demonstrated potential to be used in remedies for treating asthma and allergic reactions. " 12/01/2014 - "1,8-cineole has also shown therapeutic benefits in inflammatory airway diseases, such as asthma and chronic obstructive pulmonary disease (COPD). "
3.	Pulmonary Arterial Hypertension 01/01/2023 - "Comment on "1,8-Cineole ameliorates right ventricle dysfunction associated with pulmonary arterial hypertension by restoring connexin43 and mitochondrial homeostasis"." 01/01/2023 - "Reply to the Comment on "1,8-Cineole ameliorates right ventricle dysfunction associated with pulmonary arterial hypertension by restoring connexin43 and mitochondrial homeostasis"." 01/01/2022 - "1,8-Cineole ameliorates right ventricle dysfunction associated with pulmonary arterial hypertension by restoring connexin43 and mitochondrial homeostasis."
4.	Chronic Obstructive Pulmonary Disease (COPD) 03/01/2019 - "Since the potential effect of eucalyptol on mouse lung repair has not yet been studied, and considering that chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death worldwide, the aim of this study was to investigate eucalyptol treatment in emphysematous mice. " 03/01/2019 - "In summary, eucalyptol promoted lung repair in emphysematous mice and represents a potential therapeutic phytomedicine in the treatment of COPD." 07/22/2009 - "In this double-blind, placebo-controlled multi-center-study we randomly assigned 242 patients with stable COPD to receive 200 mg of cineole or placebo 3 times daily as concomitant therapy for 6 months during winter-time. " 07/22/2009 - "Concomitant therapy with Cineole (Eucalyptole) reduces exacerbations in COPD: a placebo-controlled double-blind trial." 07/22/2009 - "This study further suggests cineole as an active controller of airway inflammation in COPD by intervening in the pathophysiology of airway inflammation of the mucus membrane. "
5.	Inflammation (Inflammations) 11/26/2022 - "According to previous studies, 1,8-cineole might be an anti-inflammation principal compound of C. " 02/01/2014 - "The present study demonstrate the effect of pretreatment of 1,8-cineole (Cin) on inflammation induced by Aβ(25-35) in differentiated PC12 cells. " 03/24/2023 - "Therefore, we investigated the role of 1,8-cineole in colonic inflammation, using both in vivo and in vitro experimental approaches. " 01/01/2020 - "In lymphocytes from healthy human donors 1,8-cineole inhibited TNFα, IL-1β, IL-4 and IL-5 and demonstrated for the first time control of Th1/2-type inflammation. " 07/17/2019 - "Suppression of Propionibacterium acnes-Induced Skin Inflammation by Laurus nobilis Extract and Its Major Constituent Eucalyptol."

Related Drugs and Biologics

1.	Connexin 43 (Connexin43)
2.	Monoterpenes (Monoterpenoids)
3.	Eucalyptol
4.	Antioxidants
5.	Smoke
6.	Volatile Oils (Essential Oils)
7.	Limonene
8.	Cytokines
9.	Expectorants (Mucolytics)
10.	Arachidonic Acid (Vitamin F)

Related Therapies and Procedures

1.	Therapeutics
2.	Traditional Medicine (Folk Remedies)
3.	Oral Administration
4.	Airway Management
5.	Aromatherapy