Desflurane (I 653)

01/01/1999 - "The objective of the study was to determine the incidence of postoperative nausea and vomiting after general anaesthesia with desflurane. "
01/01/1999 - "Our study was designed to evaluate the effect of the combination of desflurane with N2O versus desflurane alone on postoperative nausea and vomiting (PONV) in a subgroup of female patients and PONV was considered as the primary endpoint. "
10/01/2006 - "Regression modeling demonstrated that female sex (OR=3.0, P=0.005) and use of desflurane (OR=2.8, P=0.003) were significant independent predictors of PONV. "
01/01/1999 - "The incidence of PONV was significantly higher in the group of patients receiving desflurane in N2O-O2 mixture compared with the group receiving desflurane in AIR-O2 mixture. "
09/01/1998 - "We found a significantly higher incidence of postoperative nausea and vomiting in those patients receiving desflurane. "

01/01/2006 - "We conclude that 6% desflurane, a clinically useful concentration (1 minimal alveolar concentration), improved the recovery of postsynaptic evoked responses in rat hippocampal slices after 3.5 minutes of hypoxia. "
11/01/2015 - "In this study, we aimed to assess whether desflurane preconditioning protects human umbilical vein endothelial cells (HUVECs) agaist anoxia/reoxygenation (A/R) injury. "
05/01/2008 - "In this study, ECV304 (a human umbilical vein endothelial cell line) was preconditioned with 30 min desflurane (1 minimal alveolar concentration), after 15 min washout, 30 min anoxia, and 60 min reoxygenation was performed. "
01/01/2021 - "H/R-induced cell model in L02 was established, and were treated with desflurane before hypoxia. "
11/01/2015 - "Desflurane preconditioning protects human umbilical vein endothelial cells against anoxia/reoxygenation by upregulating NLRP12 and inhibiting non-canonical nuclear factor-κB signaling."

01/01/2003 - "Animal-experimental studies demonstrate desflurane's trigger effect for malignant hyperthermia (MH). "
07/01/2003 - "Is desflurane a "weak" trigger of malignant hyperthermia?"
02/01/2001 - "[Malignant hyperthermia in a pig anesthesized with desflurane]."
04/01/1998 - "A case of suspected malignant hyperthermia during desflurane administration."
08/01/1997 - "A case of suspected malignant hyperthermia during desflurane administration."

01/01/2023 - "The primary outcome was the incidence of cough at the discontinuation of desflurane (T0) and reaching a MAC adjusted for age (MACage) of 0.15. "
01/01/2018 - "A blinded assessor noted any cough above 0.2 minimum alveolar concentration (MAC) of expired desflurane. "
03/01/2010 - "The mechanism by which cough is being triggered by desflurane should be studied to determine whether the effect is chemical or mechanical and whether it is acting in the larynx or in the distal portion of the lung."
10/01/2006 - "During this period, cough, secretion, excitation and apnea were graded and the desflurane concentration at which airway irritation symptoms first occurred was recorded. "
06/01/2015 - "Off-target effects of various drugs, such as tiotropium or desflurane, seem to produce their protective or detrimental actions on airway irritation and cough via TRPV1 and TRPA1, respectively. "

09/01/2005 - "We compared the postischemic cerebral protective effects of sevoflurane and desflurane in rats with incomplete cerebral ischemia. "
04/01/2008 - "We investigated whether halothane and desflurane affect the function of mitochondria after cerebral ischemia in rats. "
09/01/2005 - "Effects of sevoflurane and desflurane in CA1 after incomplete cerebral ischemia in rats."
04/02/2004 - "The effect of desflurane on ameliorating cerebral infarction in rats subjected to focal cerebral ischemia-reperfusion injury."
07/14/2021 - "Sevoflurane and Desflurane Exposures Following Aneurysmal Subarachnoid Hemorrhage Confer Multifaceted Protection against Delayed Cerebral Ischemia."