Chemokine CCL26

01/01/2018 - "FPP synergistically augments epithelial eotaxin-3 secretion, indicating a novel Ras-independent farnesylation mechanism or direct FPP effect that promotes epithelial eotaxin-3 production in allergic asthma."
07/01/2010 - "Since IL-4-stimulated eotaxin-3 (CCL26) secretion is a major factor in the continuous eosinophil recruitment observed in atopic asthma, our focus was to evaluate the effectiveness of blackcurrant polyphenolic compounds on CCL26 secretion in human alveolar epithelial cells. "
04/01/2006 - "[The research on the correlation between eotaxin-3 gene polymorphisms and allergic asthma]."
04/01/2006 - "To study in the linkage between eotaxin-3 gene polymorphisms and allergic asthma susceptivity, blood plasma IgE or peripheral blood eosinophil in adult population of Han nationality from Hubei province of China. "
01/01/2022 - "Pro-Th2 cytokines CCL18, TSLP, and Eotaxin-3 were elevated in AD+asthma, though not significantly higher than asthma, and elevated in asthma compared with controls. "

06/01/2008 - "This study reveals the specific association of elevated eotaxin-3 expression with high disease activity and eosinophilia in CSS patients. "
12/01/2007 - "Early studies have established that esophageal eosinophilia occurs in association with T(H)2 allergic responses, and we recently identified an EE-specific esophageal transcriptome that included eotaxin-3. "
07/01/2015 - "A difference in eotaxin-3 staining was seen in the three groups of patients with oesophageal eosinophilia. "
01/01/2014 - "In children with esophageal eosinophilia, PPIs significantly decrease eotaxin-3 expression in the proximal but not the distal esophagus. "
01/01/2018 - "PPI monotherapy in children with esophageal eosinophilia (EE) has been observed to reduce eotaxin-3 expression in epithelial cells and to practically reverse the allergy and inflammatory transcriptome. "

10/01/2011 - "Eotaxin-3 in Churg-Strauss syndrome: a clinical and immunogenetic study."
10/01/2011 - "Diagnosis of Churg-Strauss syndrome: eotaxin-3 makes it easier."
10/01/2011 - "To determine the potential of eotaxin-3 as a diagnostic marker for active disease and genetic susceptibility factor for Churg-Strauss syndrome (CSS). "
01/01/2015 - "Previous studies suggest a role for eotaxin-3, TARC/CCL17 and IgG4 in newly-diagnosed patients with eosinophilic granulomatosis with polyangiitis (EGPA, Churg-Strauss) with highly active disease. "
11/01/2016 - "Eotaxin-3 as a Biomarker of Activity in Established Eosinophilic Granulomatosis with Polyangiitis."

01/01/2014 - "Taken together, these data identify a contributory role for DNA methylation in regulating eotaxin-3 production in human allergic inflammation. "
04/15/2011 - "Herein, we identified a link between epigenetic regulation and IL-13-driven eotaxin-3 in the pathogenesis of chronic allergic inflammation. "
10/01/2006 - "We thus provide evidence that cell surface-associated eotaxin-3 is the critical IL-4-dependent chemotactic signal mediating eosinophil transepithelial migration in the setting of allergic inflammation."
09/01/2012 - "IL-13-exposed rabbits exhibited airway hyperresponsiveness, inflammation, and elevated bronchoalveolar lung fluid levels of eotaxin-3. "
12/01/2006 - "Regulatory mechanisms of galectin-9 and eotaxin-3 synthesis in epidermal keratinocytes: possible involvement of galectin-9 in dermal eosinophilia of Th1-polarized skin inflammation."

01/01/2020 - "Eosinophilic esophagitis has been linked to variations in genes like eotaxin-3, TSLP and its receptor and CAPN14, although the inheritance pattern has not yet well defined."
04/01/2010 - "We have previously proposed that the pathogenesis of eosinophilic esophagitis (EE) is mediated by an IL-13-driven epithelial cell response associated with marked gene dysregulation including eotaxin-3 overproduction. "
12/01/2007 - "In conclusion, our results highlight the important contribution of eotaxin-3 in the pathogenesis of eosinophilic esophagitis. "
02/01/2006 - "Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis."
12/01/2007 - "Increased expression of eotaxin-3 distinguishes between eosinophilic esophagitis and gastroesophageal reflux disease."