Prolotherapy

06/01/2019 - "Our study results show that prolotherapy is effective in the treatment of patients with failed rotator cuff repair surgery with significant improvements in the shoulder functions and pain relief."
10/12/2022 - "Patient A underwent prolotherapy combined with physical therapy and had significantly improved ROM after 2 weeks, with relieved pain and improved shoulder function. "
01/01/2021 - "The results showed that patients who received prolotherapy demonstrated improvement in pain (p < 0.001), mouth opening (p = 0.032), and clicking (p < 0.001), but no significant difference in deviation was observed between the groups after 1 year (p = 0.862). "
01/01/2019 - "Network meta-analysis indicated that prolotherapy significantly reduced pain compared with placebo in the long term (over 24wk; SMD: 2.63; 95% confidence interval [CI], 1.88-3.38); meanwhile PRP significantly improved shoulder function compared with placebo in the long term (over 24wk; SMD: 0.44; 95% CI, 0.05-0.84). "
10/01/2017 - "A single session of combined arthrocentesis and prolotherapy to treat symptomatic TMJ safely and significantly improved the subluxation and pain after 1 week and subluxation after 3 months compared to baseline status. "

10/01/2020 - "Prolotherapy, as an alternative therapy, has emerged as an effective treatment for chronic musculoskeletal injury, including knee osteoarthritis (OA). "
05/01/2013 - "We conducted a 3-arm, blinded (injector, assessor, injection group participants), randomized controlled trial to assess the efficacy of prolotherapy for knee osteoarthritis. "
12/01/2016 - "This study assessed the qualitative response of participants receiving prolotherapy, an injection-based complementary treatment for symptomatic knee osteoarthritis (OA). "
12/01/2016 - "Qualitative Assessment of Patients Receiving Prolotherapy for Knee Osteoarthritis in a Multimethod Study."
12/01/2023 - "Prolotherapy for knee osteoarthritis: comment on "Demonstrating the effectiveness of Platelet Rich Plasma and Prolotherapy treatments in knee osteoarthritis" by Ceylan et al."

01/01/2022 - "In these cases, adequate treatment consisting of non-biologic prolotherapy or cellular prolotherapy, including platelet rich plasma (PRP), can be beneficial in restoring spinal stability and resolving chronic low back pain."
09/01/2010 - "This study suggests that prolotherapy using a variety of proliferants can be an effective treatment for low back pain from presumed ligamentous dysfunction for some patients when performed by a skilled practitioner."
04/18/2007 - "When used alone, prolotherapy is not an effective treatment for chronic low-back pain. "
01/01/2008 - "Evidence-informed management of chronic low back pain with prolotherapy."
04/18/2007 - "There is conflicting evidence regarding the efficacy of prolotherapy injections for patients with chronic low-back pain. "

06/01/2011 - "There is also evidence to suggest that prolotherapy is effective in treating refractory tendinopathies, particularly for lateral epicondylosis and Achilles tendinopathy. "
11/09/2020 - "Sclerotherapy (ST) and prolotherapy (PT) are, among a wide range of conservative treatment options, two promising therapies and have shown positive results in other tendinopathies. "
01/01/2023 - "Prolotherapy, and percutaneous ultrasonic tenotomy and debridement are two treatment modalities that show promise in the treatment of painful, chronic tendinopathy."
01/01/2015 - "All prospective randomised and non-randomised trials, cohort studies, case-series, cross-sectional studies and controlled trials assessing the effectiveness of one or more prolotherapy injections for tendinopathy or fasciopathy at or below the superior aspect of the tibia/fibula were included. "
04/01/2011 - "Prolotherapy injections and eccentric loading exercises for painful Achilles tendinosis: a randomised trial."

03/01/2018 - "This study aims to evaluate the efficacy of prolotherapy injections for the treatment of plantar fasciitis. "
03/01/2018 - "Our study results suggest that prolotherapy is an effective auxiliary method for treating chronic plantar fasciitis."
01/01/2022 - "Comparison of Ultrasound-Guided Prolotherapy Versus Extracorporeal Shock Wave Therapy in the Treatment of Chronic Plantar Fasciitis: A Randomized Clinical Trial."
03/01/2018 - "Between October 2014 and October 2015, 60 patients with symptomatic chronic plantar fasciitis were randomly divided into two groups, as control (n=31) and prolotherapy (n=29) groups. "
03/01/2018 - "A randomized-controlled trial of prolotherapy injections in the treatment of plantar fasciitis."