Deubiquitinating Enzyme CYLD
A deubiquitinase and tumor-suppressor protein that specifically cleaves LYSINE-63-linked polyubiquitin chains and also has endodeubiquitinase activity. It functions to regulate NF-KAPPA B and WNT SIGNALING PATHWAY activity, contributing to cell survival, proliferation, and differentiation. Mutations in the CYLD gene are associated with cases of FAMILIAL CYLINDROMATOSIS.
Also Known As:
CYLD Protein; Cylindromatosis Protein; Deubiquitinating Enzyme Cylindromatosis; CYLD, Deubiquitinating Enzyme; Cylindromatosis, Deubiquitinating Enzyme
Networked: 34
relevant articles (1 outcomes,
2 trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Experts
1. | Naumann, Michael:
3 articles
(01/2017 - 01/2013)
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2. | Nishanth, Gopala:
3 articles
(01/2017 - 01/2013)
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3. | Schlüter, Dirk:
3 articles
(01/2017 - 01/2013)
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4. | Jono, Hirofumi:
3 articles
(02/2014 - 08/2007)
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5. | Hayashi, Hiroki:
2 articles
(01/2019 - 03/2008)
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6. | Nakagami, Hironori:
2 articles
(01/2019 - 03/2008)
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7. | Rakugi, Hiromi:
2 articles
(01/2019 - 03/2008)
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8. | Takami, Yoichi:
2 articles
(01/2019 - 03/2008)
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9. | Schmid, Ursula:
2 articles
(01/2017 - 05/2015)
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10. | Wang, Xu:
2 articles
(01/2017 - 05/2015)
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