Interatrial Block

Impaired or delayed impulse conduction between the right and left HEART ATRIA. Advanced interatrial blocks are often associated with arrhythmias (e.g., ATRIAL FLUTTER; and ATRIAL FIBRILLATION), direct conduction block via the Bachmann's bundle and concomitant left atrial enlargement. Syndrome of advanced interatrial block associated with SUPRAVENTRICULAR TACHYCARDIA is referred to as Bayes syndrome.

Also Known As:

Bayes Syndrome; Bayes' Syndrome; Interatrial Conduction Delay; Block, Interatrial; Conduction Delay, Interatrial; Interatrial Blocks; Interatrial Conduction Delays

Networked: 41 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Brugada Syndrome
2.	Arrhythmogenic Right Ventricular Dysplasia (Arrhythmogenic Right Ventricular Cardiomyopathy)
3.	Myocardial Infarction
4.	Bundle-Branch Block (Fascicular Block)
5.	Atrial Fibrillation

Experts

1.	Baranchuk, Adrian: 10 articles (11/2018 - 11/2008)
2.	Martínez-Sellés, Manuel: 4 articles (11/2020 - 11/2018)
3.	D'Amato, Anna: 4 articles (09/2016 - 01/2015)
4.	Marano, Marco: 4 articles (09/2016 - 01/2015)
5.	Enriquez, Andres: 4 articles (11/2015 - 04/2014)
6.	Bayés-de-Luna, Antonio: 3 articles (11/2020 - 11/2019)
7.	Escobar-Robledo, Luis Alberto: 3 articles (11/2020 - 11/2018)
8.	Hopman, Wilma: 3 articles (07/2017 - 04/2014)
9.	Conde, Diego: 3 articles (11/2015 - 04/2014)
10.	de Luna, Antoni Bayés: 3 articles (09/2015 - 04/2014)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Interatrial Block:

1.	Fluconazole (Zonal)FDA LinkGeneric 01/01/2021 - "Currently, the VCG still is superior to the ECG in specific situations, such as in the evaluation of myocardial infarctions when associated with intraventricular conduction disturbances, in the identification and location of accessory pathways in ventricular preexcitation, in the differential diagnosis of patterns varying from normal of electrical axis deviation, in the evaluation of particular aspects of Brugada syndrome, Brugada phenocopies, concealed form of arrhythmogenic right ventricular cardiomyopathy and zonal or fascicular blocks of the right bundle branch on right ventricular free wall.VCG allows us to analyze the presence of left septal fascicular block more accurately than ECG and in the diagnosis of the interatrial blocks and severity of some chambers enlargements. "
2.	Anti-Arrhythmia AgentsIBA 04/01/2014 - "The aim of our study was to assess whether advanced interatrial block (aIAB) was associated with AF recurrence after pharmacological cardioversion with two different antiarrhythmic drugs. " 07/01/1997 - "A biatrial pacemaker was inserted in a 68-year-old female with paroxysmal atrial fibrillation and atrial flutter refractory to antiarrhythmic drugs based on a sick-sinus-syndrome and concomitant interatrial conduction delay. "
3.	AnticoagulantsIBA 11/15/2018 - "Future studies must assess whether anticoagulant treatment in Bayes' Syndrome leads to better outcomes in HF."
4.	Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA 02/01/2013 - "RyR2(S/S) showed frequent sustained tachyarrhythmias, delayed afterdepolarizations and ectopic APs, increased interatrial conduction delays, reduced epicardial CVs and reduced maximum rates of AP depolarization ((dV/dt)(max)), despite similar effective refractory periods, AP durations and AP amplitudes. "
5.	CytokinesIBA 08/01/2013 - "Cardiac hemodynamics and proinflammatory cytokines during biatrial and right atrial appendage pacing in patients with interatrial block."
6.	SolutionsIBA 09/01/2011 - "This may be a solution in pacemaker patients with interatrial conduction delay."
7.	Prealbumin (Transthyretin)IBA 06/23/2021 - "The Prevalence of Advanced Interatrial Block and Its Relationship to Left Atrial Function in Patients with Transthyretin Cardiac Amyloidosis."
8.	Indicators and Reagents (Reagents)IBA 11/01/2019 - "Interatrial block (IAB) is an ECG indicator of atrial fibrosis related to atrial remodeling and thrombus formation thus leading to embolic stroke and increasing mortality. "
9.	GadoliniumIBA 01/01/2017 - "Extensive atrial fibrosis assessed by late gadolinium enhancement cardiovascular magnetic resonance associated with advanced interatrial block electrocardiogram pattern."
10.	Flecainide (Tambocor)FDA LinkGeneric 01/01/1998 - "Flecainide reduced the maximal interatrial conduction delay, but pilsicainide did not. "

Therapies and Procedures

1.	Electric Countershock (Cardioversion) 12/01/2021 - " interatrial block predicts ineffective cardioversion." 04/01/2014 - "Advanced interatrial block is associated with higher risk of AF recurrence at 1 year after pharmacological cardioversion, independent of the drug used." 11/01/2008 - "Varying P-wave morphology suggesting intermittent interatrial block (IAB) was noted after the cardioversion on the rhythm strip. " 12/01/2021 - "Advanced interatrial block predicts ineffective cardioversion of atrial fibrillation: a FinCV2 cohort study." 12/01/2018 - "Advanced interatrial block is an electrocardiographic marker for recurrence of atrial fibrillation after electrical cardioversion."
2.	Transcatheter Aortic Valve Replacement 11/17/2020 - "Our aim was to study the influence of baseline ECG parameters, including interatrial block (IAB), in the prognosis of patients treated with transcatheter aortic valve implantation. " 11/17/2020 - "Baseline ECG and Prognosis After Transcatheter Aortic Valve Implantation: The Role of Interatrial Block." 11/01/2019 - "The Baseline Interatrial block and Transcatheter aortic valve implantation (BIT) registry will be performed in approximately 3000 patients with severe AS treated with TAVI. " 11/01/2019 - "Rational and design of the Baseline Interatrial block and Transcatheter aortic valve implantation (BIT) registry." 11/17/2020 - "Methods and Results The BIT (Baseline Interatrial Block and Transcatheter Aortic Valve Implantation) registry included 2527 patients with aortic stenosis treated with transcatheter aortic valve implantation. "
3.	Catheter Ablation 01/01/2018 - "Cox regression analysis with adjustment for P-wave duration and the CHADS2 score showed that an RHR <50 beats/min (hazard ratio [HR] 1.92, 95% confidence interval [CI] 1.12 to 3.28, p = 0.017), advanced interatrial block (HR 1.82, 95% CI 1.09 to 3.04, p = 0.022), and left atrial diameter (HR 1.05, 95% CI 1.00 to 1.09, p = 0.029) were independent predictors of recurrence of AF after catheter ablation. " 07/01/2017 - "Interatrial block and interatrial septal thickness in patients with paroxysmal atrial fibrillation undergoing catheter ablation: Long-term follow-up study." 10/01/2016 - "It has been demonstrated that advanced interatrial block (IAB) is associated with an increased risk of atrial fibrillation (AF); however, the impact of advanced IAB on recurrence of paroxysmal AF after catheter ablation is not clear. " 10/01/2016 - "Advanced interatrial block predicts clinical recurrence of atrial fibrillation after catheter ablation." 01/01/2016 - "Advanced interatrial block as a predictor of atrial fibrillation following catheter ablation in the left atrium."
4.	Cardiac Resynchronization Therapy 08/01/2011 - "Right atrial appendage pacing in cardiac resynchronization therapy - haemodynamic consequences of interatrial conduction delay." 06/01/2008 - "AV junctional ablation allowing more effective delivery of cardiac resynchronization therapy in patients with intra- and interatrial conduction delay." 01/01/2020 - "Interatrial Block Predicts Atrial Fibrillation and Total Mortality in Patients with Cardiac Resynchronization Therapy." 12/01/2005 - "Spontaneous or pacing-induced interatrial conduction delay may affect the outcome of heart failure patients treated with cardiac resynchronization therapy (CRT). " 11/01/2015 - "Advanced Interatrial Block Predicts New Onset Atrial Fibrillation in Patients with Severe Heart Failure and Cardiac Resynchronization Therapy."
5.	Renal Dialysis (Hemodialysis) 09/01/2016 - "A chronic hemodialysis patient-known to have advanced interatrial block (IAB)-had reported symptoms suggesting arrhythmias, hence she underwent hemodialysis treatment while on the cardiac monitor. " 04/01/2016 - "Advanced interatrial block in hemodialysis patients." 03/01/2015 - "Prevalence and determinants of interatrial block in hemodialysis patients." 01/01/2015 - "Left atrial dynamic function and interatrial block in hemodialysis patients: the importance of P-wave morphology analysis." 01/01/2015 - "Second-degree interatrial block in hemodialysis patients."