DEAD Box Protein 58
A DEAD-box RNA helicase that contains an N-terminal DEATH-LIKE DOMAIN, AAA+ ATPase domain, and C-terminal RNA HELICASE activity. It functions as an innate immune receptor through its recognition of viral nucleic acids. It also induces the expression of INTERFERON TYPE I and proinflammatory CYTOKINES. Its ligands include: 5'-triphosphorylated SINGLE-STRANDED RNA, DOUBLE-STRANDED RNA (dsRNA), and short dsRNA (less than 1 kb in length).
Also Known As:
DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58; Probable ATP-Dependent RNA Helicase DDX58; RIG-I-like Receptor 1; Probable ATP Dependent RNA Helicase DDX58; RIG I like Receptor 1
Networked: 4
relevant articles (0 outcomes,
1 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Cui, Jun:
1 article
(01/2020)
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2. | Jin, Shouheng:
1 article
(01/2020)
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3. | Xian, Huifang:
1 article
(01/2020)
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4. | Yang, Shuai:
1 article
(01/2020)
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5. | Zhang, Yuxia:
1 article
(01/2020)
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6. | Bendtzen, K:
1 article
(10/2014)
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7. | Enevold, C:
1 article
(10/2014)
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8. | Hermansen, M L F:
1 article
(10/2014)
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9. | Jacobsen, R S:
1 article
(10/2014)
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10. | Jacobsen, S:
1 article
(10/2014)
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