Trefoil Factors
A family of small peptides expressed primarily by MUCOUS MEMBRANE EPITHELIAL CELLS in vertebrates. Their structure is highly conserved and is defined by a three-leaved (trefoil) domain of 42 or 43 amino acids; it includes six cysteines that create the trefoil structure through disulfide bridges. Trefoil peptides may form dimers with each other, or associate with MUCINS and other factors. They are important for maintaining epithelial integrity and for protection from noxious agents.
Also Known As:
TFF Peptides; Trefoil Factor Family Peptides; Trefoil Factor Family Proteins; Trefoil Peptides; Trefoil Proteins; Factor, Trefoil; Peptide, TFF; Peptide, Trefoil; Protein, Trefoil; TFF Peptide; Trefoil Factor; Trefoil Peptide; Trefoil Protein
Networked: 301
relevant articles (3 outcomes,
34 trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Experts
1. | May, Felicity E B:
12 articles
(06/2012 - 04/2002)
|
2. | Hoffmann, Werner:
10 articles
(11/2021 - 01/2002)
|
3. | Thim, Lars:
10 articles
(07/2015 - 01/2003)
|
4. | Zhang, Yun:
10 articles
(01/2015 - 05/2005)
|
5. | Westley, Bruce R:
10 articles
(03/2009 - 04/2002)
|
6. | Ohmoto, Yasukazu:
9 articles
(01/2021 - 06/2011)
|
7. | Giraud, Andrew S:
8 articles
(09/2016 - 05/2004)
|
8. | Dünker, Nicole:
7 articles
(08/2019 - 02/2013)
|
9. | St-Amand, Jonny:
6 articles
(12/2021 - 07/2013)
|
10. | Yoshioka, Mayumi:
6 articles
(12/2021 - 07/2013)
|
Related Diseases
Related Drugs and Biologics
Related Therapies and Procedures