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ODN M362

a TLR9 agonist with antineoplastic activity Sequence = 5’-tcgtcgtcgttc:gaacgacgttgat-3

Also Known As:

ODN M362 sodium

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleotides: 15763
  - Polynucleotides: 218
    - Oligonucleotides: 5145
      - Oligodeoxyribonucleotides: 2217
        ODN M362: 2

Experts

1.	Abbas, Flora: 1 article (06/2022)
2.	Apoil, Pol André: 1 article (06/2022)
3.	Blancher, Antoine: 1 article (06/2022)
4.	Cenac, Claire: 1 article (06/2022)
5.	Congy-Jolivet, Nicolas: 1 article (06/2022)
6.	Dellacasagrande, Jérôme: 1 article (06/2022)
7.	Guedj, Kevin: 1 article (06/2022)
8.	Guyonnet, Sophie: 1 article (06/2022)
9.	Guéry, Jean-Charles: 1 article (06/2022)
10.	Laffont, Sophie: 1 article (06/2022)

Related Diseases

1.	Neoplasms (Cancer) 10/01/2008 - "We showed previously that treatment with the TLR9-agonistic ODN M362 (a CpG sequence containing oligonucleotide) induces matrix metalloproteinase-13-mediated invasion in TLR9-expressing human cancer cell lines. "
2.	Bites and Stings (Sting) 06/01/2022 - "In a large cohort of individuals from 19 to 97 years old, we measured the production of IFN-α and inflammatory cytokines in whole-blood upon stimulation with either R-848, ODN M362 CpG-C, or cGAMP, which activate the TLR7/8, TLR9 or STING pathways, respectively. "

Related Drugs and Biologics

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