Ly101-4B

inhibits expression of heat shock factor 1; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Ovarian Neoplasms (Ovarian Cancer) 12/01/2013 - "These findings demonstrate that Ly101-4B is a promising candidate for ovarian cancer therapy, and expand our understanding of HSF1, by revealing that it can regulate microRNA biogenesis in addition to its canonical function of regulating protein-coding RNAs."
2.	Neoplasms (Cancer) 12/01/2013 - "Moreover, by targeting HSF1, Ly101-4B inhibits the biogenesis of microRNA-214, which has been revealed to be overexpressed and to promote cell survival in human ovarian epithelial tumors. "

1.	Therapeutics