bis-N-norgliovictin

structure in first source

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Inorganic Chemicals: 9
- Electrolytes: 16106
  - Ions: 7857
    - Anions: 3501
      - Sulfides: 1062
        bis-N-norgliovictin: 1
- Sulfur Compounds: 278
  - Hydrogen Sulfide: 2764
    - Sulfides: 1062
      - bis-N-norgliovictin: 1
Organic Chemicals: 133
- Sulfur Compounds: 278
  - Sulfides: 1062
    - bis-N-norgliovictin: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperazines: 26
    - Diketopiperazines: 59
      - bis-N-norgliovictin: 1

Experts

1.	Dou, Huan: 1 article (04/2013)
2.	Gong, Wei: 1 article (04/2013)
3.	Hou, Yayi: 1 article (04/2013)
4.	Li, Erguang: 1 article (04/2013)
5.	Liu, Xianqin: 1 article (04/2013)
6.	Song, Yuxian: 1 article (04/2013)
7.	Tan, Renxiang: 1 article (04/2013)
8.	Yu, Zhiguo: 1 article (04/2013)

Related Diseases

1.	Sepsis (Septicemia) 04/05/2013 - "These findings suggest that bis-N-norgliovictin can be a useful therapeutic candidate for the treatment of sepsis and other inflammatory diseases." 04/05/2013 - "In this study, we evaluated the effect of bis-N-norgliovictin on TLR4-mediated inflammation in mouse macrophages and LPS-induced sepsis model. " 04/05/2013 - "Bis-N-norgliovictin, a small-molecule compound from marine fungus, inhibits LPS-induced inflammation in macrophages and improves survival in sepsis."
2.	Inflammation (Inflammations) 04/05/2013 - "In this study, we evaluated the effect of bis-N-norgliovictin on TLR4-mediated inflammation in mouse macrophages and LPS-induced sepsis model. " 04/05/2013 - "Bis-N-norgliovictin, a small-molecule compound from marine fungus, inhibits LPS-induced inflammation in macrophages and improves survival in sepsis." 04/05/2013 - "During the screening of natural products against inflammation, we identified bis-N-norgliovictin, a small-molecule compound isolated from marine-derived fungus, significantly inhibited lipopolysaccharide (LPS, ligand of TLR4)-induced tumor necrosis factor-α (TNF-α) production in RAW264.7 cells. "
3.	Lung Injury 04/05/2013 - "Intravenous injection of bis-N-norgliovictin 1h before LPS challenge dose-dependently inhibited LPS-induced increases in serum levels of TNF-α, IL-6, MCP-1 and IL-10, attenuated liver and lung injury and diminished M1 macrophage polarization in liver. "
4.	Shock 04/05/2013 - "Importantly, bis-N-norgliovictin also protected mice against LPS-induced endotoxic shock. "

Related Drugs and Biologics

1.	Interleukin-10 (Interleukin 10)
2.	Interleukin-6 (Interleukin 6)
3.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
4.	Lipopolysaccharides
5.	Ligands

Related Therapies and Procedures

1.	Intravenous Injections