salecan

09/01/2011 - "Based on the results from the subchronic study, the overall health, body weight gain, food consumption and clinical pathology parameters were comparable between the groups feed Salecan and the control. "
03/20/2013 - "ICR mice were administrated intragastrically (i.g.) by gavage with 100, 200 and 300 mg/kg body weight (BW) of Salecan while the control mice were received saline. "
09/01/2011 - "The oral LD50 of Salecan in ICR mice was greater than 3000 mg/kg body weight. "
01/01/2019 - "Orally administration of salecan improved the severity of intestinal mucositis in a dose-dependent manner, as evidenced by the well-maintained mucosal architecture and body weight in salecan-treated groups. "
01/28/2013 - "After 6 weeks, mice fed 2 and 5 % Salecan had significantly lower body weight, fat mass and percentage of body fat mass compared with those fed a high-fat cellulose (control) diet. "

11/01/2014 - "The unique chemical composition and excellent physicochemical properties make Salecan a promising material for applications in coagulation, lubrication, protection against acute liver injury, and alleviating constipation. "
03/20/2013 - "The aim of the present study was to evaluate the effects of Salecan on fecal output and small intestinal transit in normal and two models of drug-induced constipation mice. "
03/20/2013 - "In two models of drug-induced constipation, Salecan dose-dependently restored the fecal number and fecal weight. "
03/20/2013 - "These results suggest that Salecan has a potential to be used as a hydrophilic laxative for constipation."
03/20/2013 - "Treatment with Salecan significantly raised the fecal water content in loperamide-induced constipation mice. "

05/28/2014 - "Male C57BL/6J mice were fed a diet supplemented with either 4 or 8 % Salecan for 26 d and DSS was administered to induce acute colitis during the last 5 d of the experimental period. "
05/28/2014 - "The results indicated that the dietary incorporation of Salecan attenuated the severity of DSS colitis as evidenced by the decreased disease activity index, reduced severity of anaemia, attenuated changes in colon architecture and reduced colonic myeloperoxidase activity. "
05/28/2014 - "In conclusion, the present study suggests that Salecan contributes to the reduction of colonic damage and inflammation in mice with DSS-induced colitis and holds promise as a new, effective nutritional supplement in the management of inflammatory bowel disease. "
05/28/2014 - "The aims of the present study were to investigate the protective effects of a Salecan diet in the well-defined dextran sulphate sodium (DSS) model of experimental murine colitis and to elucidate the mechanism involved in its effects with special attention being paid to its effect on the production of TNF-α, a primary mediator involved in the inflammatory response. "
05/28/2014 - "Supplementation of the diet with Salecan attenuates the symptoms of colitis induced by dextran sulphate sodium in mice."

01/01/2019 - "Metabolomics analysis revealed that salecan treatment reversed the intestinal metabolic profiling changes in mice with MTX-induced mucositis. "
01/01/2019 - "Orally administration of salecan improved the severity of intestinal mucositis in a dose-dependent manner, as evidenced by the well-maintained mucosal architecture and body weight in salecan-treated groups. "
01/01/2019 - "Orally administered salecan ameliorates methotrexate-induced intestinal mucositis in mice."
01/01/2019 - "Salecan has potential advantages in the treatment of MTX-induced intestinal mucositis, and its protective effect is mainly attributed to its antioxidant and immunomodulatory properties."

05/28/2014 - "In conclusion, the present study suggests that Salecan contributes to the reduction of colonic damage and inflammation in mice with DSS-induced colitis and holds promise as a new, effective nutritional supplement in the management of inflammatory bowel disease. "