HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

KOS-1584

structure in first source

Networked: 6 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Lactones: 1549
  - Polyketides: 231
    - Macrolides: 4391
      - Epothilones: 223
        KOS-1584: 6

Experts

1.	Vahdat, Linda: 2 articles (12/2008 - 03/2008)
2.	Vahdat, Linda T: 2 articles (04/2008 - 04/2008)
3.	Baggio Gnoatto, Simone Cristina: 1 article (09/2013)
4.	Bergold, Ana Maria: 1 article (09/2013)
5.	Froehlich, Pedro Eduardo: 1 article (09/2013)
6.	Kaiser, Samuel: 1 article (09/2013)
7.	Muller, Joseane John: 1 article (09/2013)
8.	Cropp, Gillian F: 1 article (02/2012)
9.	Goel, Sanjay: 1 article (02/2012)
10.	Haley, Brandi I: 1 article (02/2012)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 09/01/2013 - "Sagopilone, desoxiepothilone and KOS-1584 are in phase II clinical trials, for the treatment of recurrent glioblastoma and advanced metastatic breast cancer, metastasic breast cancer and metastatic pulmonary cancer, respectively. " 04/01/2008 - "Other epothilones currently in clinical studies are KOS-862, patupilone, ZK-EPO, BMS-310705, and KOS-1584, which have all shown activity in patients with pretreated or resistant metastatic breast cancer." 12/01/2008 - "Other epothilones such as KOS-862, patupilone, ZK-EPO, BMS-310705, and KOS-1584 are being evaluated as therapy for patients with breast cancer, with promising preliminary data. "
2.	Neoplasms (Cancer) 02/01/2012 - "Patients with advanced solid malignancies received KOS-1584 every 3 weeks until disease progression. " 02/01/2012 - "Phase I dose escalation study of KOS-1584, a novel epothilone, in patients with advanced solid tumors." 03/01/2008 - "Other epothilones, such as patupilone, KOS-1584, and ZK-EPO, are also being evaluated in drug-resistant cancers. " 04/15/2008 - "Several epothilone compounds, including ixabepilone (BMS-247550, aza-epothilone B, Ixempra), patupilone (EPO906, epothilone B), KOS-862 (desoxyepothilone B, epothilone D), BMS-310705, ZK-EPO (ZK-219477), nd KOS-1584, have been testedf or the treatment of a variety of solid tumor types. "
3.	Lung Neoplasms (Lung Cancer) 09/01/2013 - "Sagopilone, desoxiepothilone and KOS-1584 are in phase II clinical trials, for the treatment of recurrent glioblastoma and advanced metastatic breast cancer, metastasic breast cancer and metastatic pulmonary cancer, respectively. "
4.	Glioblastoma (Glioblastoma Multiforme) 09/01/2013 - "Sagopilone, desoxiepothilone and KOS-1584 are in phase II clinical trials, for the treatment of recurrent glioblastoma and advanced metastatic breast cancer, metastasic breast cancer and metastatic pulmonary cancer, respectively. "
5.	Disease Progression 02/01/2012 - "Patients with advanced solid malignancies received KOS-1584 every 3 weeks until disease progression. "

Related Drugs and Biologics

1.	Epothilones (Epothilone)
2.	sagopilone
3.	epothilone B (EPO906)
4.	desoxyepothilone B (epothilone D)
5.	ixabepilone (BMS 247550)

Related Therapies and Procedures

1.	Therapeutics