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ETC 642

a complex of ESP-24218 and the above lipids that mimics apoA-I; has anti-inflammatory activity

Also Known As:

ETC-642; ETC642

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Bao, Shisan: 1 article (11/2011)
2.	Barter, Philip J: 1 article (11/2011)
3.	Bursill, Christina A: 1 article (11/2011)
4.	Di Bartolo, Belinda A: 1 article (11/2011)
5.	Rye, Kerry-Anne: 1 article (11/2011)
6.	Tan, Joanne Tm: 1 article (11/2011)
7.	Vanags, Laura Z: 1 article (11/2011)
8.	Imaizumi, Satoshi: 1 article (10/2011)
9.	Iwata, Atsushi: 1 article (10/2011)
10.	Miura, Shin-ichiro: 1 article (10/2011)

Related Diseases

1.	Inflammation (Inflammations) 11/30/2011 - "Infusion of ETC-642 causes anti-inflammatory effects that are comparable to rHDL in an animal model of chronic vascular inflammation and highlights that apoA-I mimetic peptides present a viable strategy for the treatment of inflammatory disease." 11/30/2011 - "The apolipoprotein A-I mimetic peptide, ETC-642, reduces chronic vascular inflammation in the rabbit." 11/30/2011 - "This study aimed to compare the anti-inflammatory effects of ETC-642, an apoA-I mimetic peptide, with that of discoidal reconstituted HDL (rHDL), consisting of full-length apoA-I complexed with phosphatidylcholine, in rabbits with chronic vascular inflammation. "
2.	Atherosclerosis 10/01/2011 - "In WHHL rabbits, high-dose ETC-642 inhibited the progression of aortic atherosclerosis compared to placebo. "
3.	Prostatic Neoplasms (Prostate Cancer) 07/01/2004 - ".TNF.11D, adefovir dipivoxil, AdPEDF.11, AES-14, albumex, alefacept, alemtuzumab, aliskiren fumarate, alvimopan hydrate, aAminolevulinic acid hydrochloride, aminolevulinic acid methyl ester, anakinra, anti-IL-12 MAb, aprepitant, atazanavir sulfate, atrasentan, avanafil; Banoxantrone, BG-12, bimatoprost, bortezomib, bosentan; Calcipotriol/betamethasone dipropionate, caspofungin acetate, CBT-1, ciclesonide, clofarabine, conivaptan hydrochloride, CpG-7909, C-Vax, Cypher; DA-8159, DAC:GLP-1, darbepoetin alfa, darifenacin, duloxetine hydrochloride; Eculizumab, efalizumab, efaproxiral sodium, EGF vaccine, eletriptan, epratuzumab, erlotinib hydrochloride, escitalopram oxalate, ETC-642, etoricoxib, everolimus, exenatide; Gefitinib, IV gamma-globulin; Human insulin, gamma-hydroxybutyrate sodium; IDN-6556, iguratimod, imatinib mesylate, indiplon, ixabepilone; Laquinimod, LB-80380, lidocaine/prilocaineliraglutide, lopinavir, lopinavir/ritonavir, lucinactant; MAb-14.18, melatonin, MLN-591-DM1; NC-531, neridronic acid, nesiritide, neutrophil-inhibitory factor, niacin/lovastatin; Oblimersen sodium, olcegepant, oral Insulin, ORV-105; Palonosetron hydrochloride, PAmAb, pegaptanib sodium, peginterferon alfa-2a, pegvisomant, perifosine, pexelizumab, phenoxodiol, phenserine tartrate, pimecrolimus, pramlintide acetate, pregabalin, PRO-542, prostate cancer vaccine, PT-141; Ramelteon, rasagiline mesilate, rDNA insulin, reslizumab, rh-Lactoferrin, ribamidine hydrochloride, rosuvastatin calcium; S-8184l, SC-1, sorafenib, St. John's Wort extract, SU-11248; Taxus, telbivudine, tenofovir disoproxil fumarate, teriparatide, testosterone gel, tezosentan disodium, tipifarnib, tolvaptan, trabectedin, travoprost, travoprost/timolol, treprostinil sodium; Vardenafil hydrochloride hydrate; Xcellerated T cells, XR-5944; Yttrium 90 (90Y) ibritumomab tiuxetan; Ziconotide."

Related Drugs and Biologics

1.	Apolipoprotein A-I (Apolipoprotein A1)
2.	Phosphatidylcholines (Phosphatidylcholine)
3.	Peptides (Polypeptides)
4.	Lopinavir
5.	Interleukin 1 Receptor Antagonist Protein (Anakinra)
6.	Glucagon-Like Peptide 1 (GLP 1)
7.	Brain Natriuretic Peptide (Natrecor)
8.	Ritonavir (Norvir)
9.	Teriparatide (Parathar)
10.	Yttrium