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N- (4- (4- (morpholine- 4- carbonyl)piperidine- 1- yl)phenyl)- 2- phenoxypyrimidine- 5- carboxamide

inhibits hematopoietic prostaglandin D synthase; structure in first source

Also Known As:

TFC 007; TFC-007; TFC007

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - N-(4-(4-(morpholine-4-carbonyl)piperidine-1-yl)phenyl)-2-phenoxypyrimidine-5-carboxamide: 2
  - Oxazines: 9
    - Morpholines: 6
      - N-(4-(4-(morpholine-4-carbonyl)piperidine-1-yl)phenyl)-2-phenoxypyrimidine-5-carboxamide: 2

Experts

1.	Aritake, Kosuke: 1 article (11/2021)
2.	Demizu, Yosuke: 1 article (11/2021)
3.	Endo, Akinori: 1 article (11/2021)
4.	Fujii, Kiyonaga: 1 article (11/2021)
5.	Hamamura, Kengo: 1 article (11/2021)
6.	Ito, Takahito: 1 article (11/2021)
7.	Murakami, Yuki: 1 article (11/2021)
8.	Naito, Mikihiko: 1 article (11/2021)
9.	Saeki, Yasushi: 1 article (11/2021)
10.	Shibata, Norihito: 1 article (11/2021)

Related Diseases

1.	Allergic Rhinitis 08/01/2011 - "We evaluated the effects of a selective H-PGDS inhibitor, TFC-007, on nasal symptoms on Japanese cedar pollen-induced allergic rhinitis of guinea pigs. "
2.	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 11/11/2021 - "Additionally, in a Duchenne muscular dystrophy model using mdx mice with cardiac hypertrophy, compound 6 showed better inhibition of inflammatory cytokines than a potent H-PGDS inhibitor TFC-007. "
3.	Cardiomegaly (Heart Hypertrophy) 11/11/2021 - "Additionally, in a Duchenne muscular dystrophy model using mdx mice with cardiac hypertrophy, compound 6 showed better inhibition of inflammatory cytokines than a potent H-PGDS inhibitor TFC-007. "

Related Drugs and Biologics

1.	Cytokines