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Cowden-Like Syndrome

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Neoplasms: 1324753
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Inborn Genetic Diseases: 11939
  - Hereditary Neoplastic Syndromes: 112
    - Multiple Hamartoma Syndrome: 259
      - Cowden-Like Syndrome: 3
Nutritional and Metabolic Diseases: 15
- Metabolic Diseases: 10142
  - Mitochondrial Diseases: 21919
    - Cowden-Like Syndrome: 3

Related Diseases

1.	Multiple Hamartoma Syndrome (Cowden's Disease)
2.	Thyroid Neoplasms (Thyroid Cancer)
3.	Neoplasms (Cancer)

Experts

1.	Eng, Charis: 3 articles (11/2012 - 12/2010)
2.	He, Xin: 2 articles (11/2012 - 01/2012)
3.	Ringel, Matthew D: 2 articles (11/2012 - 01/2012)
4.	Mester, Jessica: 2 articles (01/2012 - 12/2010)
5.	Ngeow, Joanne: 1 article (11/2012)
6.	Radhakrishnan, Deepa: 1 article (11/2012)
7.	Romigh, Todd: 1 article (11/2012)
8.	Saji, Motoyasu: 1 article (11/2012)
9.	Wang, Yu: 1 article (11/2012)
10.	Yu, Qi: 1 article (11/2012)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Cowden-Like Syndrome:

1.	Phosphoric Monoester Hydrolases (Phosphatases)IBA 11/01/2012 - "Germline mutations in PTEN are associated with phosphatase and tensin homolog deleted on chromosome 10 (PTEN) hamartoma tumor syndrome including Cowden syndrome (CS) and Cowden-like syndrome (CSL) that predisposes to high risks of benign and malignant tumors of thyroid and breast. "
2.	Nucleic AcidsIBA 12/22/2010 - "Nucleic acids from prospective nested series of 123 patients with Cowden syndrome or Cowden-like syndrome and 50 unaffected individuals without PTEN variants were analyzed for germline methylation and expression of PTEN and KILLIN at the Cleveland Clinic, August 2008-June 2010. "
3.	NAD (NADH)IBA 01/15/2012 - "Germline SDHx variants modify breast and thyroid cancer risks in Cowden and Cowden-like syndrome via FAD/NAD-dependant destabilization of p53."
4.	Flavin-Adenine Dinucleotide (FAD)IBA 01/15/2012 - "Germline SDHx variants modify breast and thyroid cancer risks in Cowden and Cowden-like syndrome via FAD/NAD-dependant destabilization of p53."
5.	TensinsIBA 11/01/2012 - "Germline mutations in PTEN are associated with phosphatase and tensin homolog deleted on chromosome 10 (PTEN) hamartoma tumor syndrome including Cowden syndrome (CS) and Cowden-like syndrome (CSL) that predisposes to high risks of benign and malignant tumors of thyroid and breast. "