Multiple Endocrine Neoplasia

A group of autosomal dominant diseases characterized by the combined occurrence of tumors involving two or more ENDOCRINE GLANDS that secrete PEPTIDE HORMONES or AMINES. These neoplasias are often benign but can be malignant. They are classified by the endocrine glands involved and the degree of aggressiveness. The two major forms are MEN1 and MEN2 with gene mutations on CHROMOSOME 11 and CHROMOSOME 10, respectively.

Also Known As:

Multiple Endocrine Adenomatosis; Adenomatosis, Multiple Endocrine; Familial Endocrine Adenomatosis; Multiple Endocrine Adenopathy; Multiple Endocrine Neoplasia Syndromes; Multiple Endocrine Neoplasms; Adenomatoses, Familial Endocrine; Adenomatoses, Multiple Endocrine; Adenopathies, Multiple Endocrine; Adenopathy, Multiple Endocrine; Endocrine Adenomatoses, Familial; Endocrine Adenomatoses, Multiple; Endocrine Adenomatosis, Familial; Endocrine Adenomatosis, Multiple; Endocrine Adenopathies, Multiple; Endocrine Adenopathy, Multiple; Endocrine Neoplasms, Multiple; Familial Endocrine Adenomatoses; Multiple Endocrine Adenomatoses; Multiple Endocrine Adenopathies; Adenomatosis, Familial Endocrine; Endocrine Neoplasia, Multiple; Multiple Endocrine Neoplasia Syndrome; Neoplasia, Multiple Endocrine; Neoplasms, Multiple Endocrine

Neoplasms: 1324753
- Hereditary Neoplastic Syndromes: 112
  - Multiple Endocrine Neoplasia: 504
- Multiple Primary Neoplasms: 24
  - Multiple Endocrine Neoplasia: 504
- Neoplasms by Site: 4
  - Endocrine Gland Neoplasms: 130
    - Multiple Endocrine Neoplasia: 504
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Inborn Genetic Diseases: 11939
  - Hereditary Neoplastic Syndromes: 112
    - Multiple Endocrine Neoplasia: 504
Endocrine System Diseases: 968
- Endocrine Gland Neoplasms: 130
  - Multiple Endocrine Neoplasia: 504

Type IV Multiple Endocrine Neoplasia

Disease Context: Research Results