cyclopia sequence

01/01/2023 - "The antifungal activities of rooibos (Aspalathus linearis) and honeybush (Cyclopia species) tea extracts reduced the growth of plant pathogen Botrytis cinerea, but their efficacy against Fusarium spp. is unknown. "
01/01/2013 - "In this study three extracts, P104, SM6Met, and cup-of-tea, from two species of Cyclopia, C. "
09/01/2023 - "A hot water extract of green Cyclopia subternata, also used as honeybush tea, was selected as the main ingredient because it provides different types of phenolic compounds associated with bioactive properties (i.e. "
01/01/2023 - "linearis), honeybush (Cyclopia subternata), and green tea (Camellia sinensis) on 10 Fusarium strains."
01/01/2023 - "linearis) and honeybush (Cyclopia subternata) aqueous extracts as well as green tea (Camellia sinensis) against 10 Fusarium species. "

07/01/2009 - "The rapid clearance of cyclopamine indicates that ingestion of V. californicum must occur during a very narrow window for synophthalmia formation to occur. "
04/01/2012 - "In zebrafish embryos a typical phenotype (cyclopia) associated with Shh interference was only observed for cyclopamine. "
07/01/2009 - "The critical window for cyclopamine-induced synophthalmia formation has been reported to be gestational day (GD) 14. "
07/01/2009 - "Cyclopamine-induced synophthalmia in sheep: defining a critical window and toxicokinetic evaluation."
11/01/1989 - "Embryos were affected in five of seven ewes dosed cyclopamine orally at higher levels (four nonpregnant and one with cyclopia). "

02/13/2008 - "However, the presence of high levels of mangiferin merits the use of Cyclopia spp. and, in particular, C. "
10/29/2021 - "Mangiferin and Hesperidin Transdermal Distribution and Permeability through the Skin from Solutions and Honeybush Extracts (Cyclopia sp.)-A Comparison Ex Vivo Study."
12/01/2008 - "The aim of this study was to determine the concentrations of mangiferin, hesperidin, and their metabolites in plasma, urine, and feces samples from pigs consuming an extract of Cyclopia genistoides. "
11/07/2022 - "Mangiferin (MGF) is a natural and valuable polyphenol found in significant levels in many plant species, including Cyclopia intermedia (C. "
10/29/2021 - "Polyphenolic compounds-mangiferin and hesperidin-are, among others, the most important secondary metabolites of African shrub Cyclopia sp. (honeybush). "

05/19/2023 - "Cyclopia sp. (honeybush) is an African shrub known as a rich source of polyphenols. "
01/01/2018 - "Polyphenol-Enriched Fractions of Cyclopia intermedia Selectively Affect Lipogenesis and Lipolysis in 3T3-L1 Adipocytes."
05/01/2013 - "This minireview presents an overview of polyphenols found in Cyclopia and focuses on the phytoestrogenic potential of selected polyphenols and of extracts prepared from the plant."
05/01/2013 - "Phytoestrogenic potential of Cyclopia extracts and polyphenols."
05/30/2007 - "HPLC and LC-MS analysis, however, suggests that the observed phytoestrogenic activity cannot be ascribed to polyphenols known to be present in other Cyclopia species."

04/01/2021 - "3-β-D-Glucopyranosylmaclurin, a minor benzophenone, was the least stable of the compounds, degrading faster in the benzophenone-enriched fraction than in ultrafiltered Cyclopia genistoides extract, suggesting that the ultrafiltered extract matrix may provide a degree of protection against chemical degradation. "
03/01/2014 - "The benzophenone, iriflophenone-3-C-glucoside, was isolated from Cyclopia genistoides using a combination of fluid-fluid extraction, high performance counter-current chromatography (HPCCC) and semi-preparative high performance liquid chromatography (HPLC). "
04/01/2021 - "Hygroscopicity of the powders, indicated by moisture uptake, decreased in the order: benzophenone-enriched fraction (22.7%) > ultrafiltered Cyclopia genistoides extract (14.0%) > xanthone-enriched fraction (10.7%). "
04/01/2021 - "Storage stability testing and moisture sorption assays of the xanthone-enriched fraction, benzophenone-enriched fraction, and ultrafiltered Cyclopia genistoides extract were performed to determine their susceptibility to physical and chemical degradation during storage. "
09/15/2019 - "Ultrafiltration of Cyclopia genistoides extract was optimised to increase its benzophenone and xanthone content as quantified using HPLC-DAD. "

01/01/2023 - "Introduction: Rooibos (Aspalathin linearis), honeybush (Cyclopia intermedia), and sutherlandia (Sutherlandia frutescene) are three Southern Africa indigenous plants, of which the extracts have become house-hold items and are consumed on a large scale. "
01/01/2023 - "The effect of Aspalathin linearis, Cyclopia intermedia and Sutherlandia frutescene on sperm functional parameters of healthy male wistar rats."
12/10/2006 - "Aspalathin and mangiferin, major polyphenols in rooibos and Cyclopia spp., respectively, exhibited weak to moderate protective effects when compared to the major green tea catechin, (-)epigallocatechin gallate (EGCG). "

12/10/2006 - "Aspalathin and mangiferin, major polyphenols in rooibos and Cyclopia spp., respectively, exhibited weak to moderate protective effects when compared to the major green tea catechin, (-)epigallocatechin gallate (EGCG). "

12/10/2006 - "Aspalathin and mangiferin, major polyphenols in rooibos and Cyclopia spp., respectively, exhibited weak to moderate protective effects when compared to the major green tea catechin, (-)epigallocatechin gallate (EGCG). "

01/01/2014 - "In this study, we used real-time cytotoxicity cellular analysis of the Cyclopia sp. extracts on HeLa cells and found that the higher hesperidin content in non-fermented "green" extracts correlated with their higher cytotoxicity compared to the fermented extracts. "
07/01/2009 - "subternata callus was characterized by the best growth parameters and highest hesperidin content (0.69%) from all examined Cyclopia calli."
10/29/2021 - "Mangiferin and Hesperidin Transdermal Distribution and Permeability through the Skin from Solutions and Honeybush Extracts (Cyclopia sp.)-A Comparison Ex Vivo Study."
12/01/2008 - "The aim of this study was to determine the concentrations of mangiferin, hesperidin, and their metabolites in plasma, urine, and feces samples from pigs consuming an extract of Cyclopia genistoides. "
10/29/2021 - "Polyphenolic compounds-mangiferin and hesperidin-are, among others, the most important secondary metabolites of African shrub Cyclopia sp. (honeybush). "

09/01/2016 - "Flavonoids from Cyclopia genistoides and Their Xanthine Oxidase Inhibitory Activity."
03/01/2016 - "Thus, in this study, we attempted to determine whether 2 structurally related flavonoids found in Cyclopia subternata, vicenin-2 and scolymoside, can suppress high-glucose (HG)-induced vascular inflammatory processes in human umbilical vein endothelial cells (HUVECs) and mice. "
12/01/2015 - "Two structurally related flavonoids found in Cyclopia subternata, namely vicenin-2 and scolymoside, were examined for its effects on inflammatory responses by monitoring the effects of vicenin-2 and scolymoside on lipopolysaccharide (LPS)-mediated vascular inflammatory responses. "
01/01/2020 - "The aim of this study was to investigate the effects of two structurally related flavonoids found in Cyclopia subternata, vicenin-2 (VCN) and scolymoside (SCL) on lipopolysaccharide (LPS)-induced liver failure in mice and to elucidate underlying mechanisms. "

10/01/2018 - "This randomized, double-blinded, placebo-controlled study aimed to evaluate the efficacy and safety of fermented honeybush (Cyclopia intermedia) extract (HU-018) for skin rejuvenation. "

03/01/2018 - "This study is the first reporting immunostimulatory activity for Cyclopia, which are widely consumed as the herbal tea known as honeybush, underpinning further investigations into the potential use of its extracts as adjuvants for mucosal immunotherapy."

03/01/2016 - "Cyclopia subternata is a medicinal plant commonly used in traditional medicine to relieve pain in biological processes. "
12/01/2015 - "Cyclopia subternata is a medicinal plant commonly used in traditional medicine to relieve pain in biological processes. "
10/01/2015 - "Cyclopia subternata is a medicinal plant commonly used in traditional medicine to relieve pain. "
09/01/2015 - "Cyclopia subternata is a medicinal plant commonly used in traditional medicine to relieve pain in physiological processes. "
08/01/2015 - "Cyclopia subternata is a medicinal plant commonly used in traditional medicine to relieve pain. "

01/01/2018 - "Chemoprevention of LA7-Induced Mammary Tumor Growth by SM6Met, a Well-Characterized Cyclopia Extract."
10/01/2016 - "SM6Met, a phytoestrogenic extract of Cyclopia subternata indigenous to the Western Cape province of South Africa, displays estrogenic attributes with potential for breast cancer chemoprevention. "

01/01/1997 - "[Cataract surgery with intraocular lens implantation in cyclopia patients]."