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acetyl-arginyl-glutamyl-arginine
protects against Abeta-induced memory loss in young chicks
Also Known As:
Ac-RER; D-Arg-L-Glu-D-Arg; acetyl-Arg-Glu-Arg
Networked:
1
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Peptides: 82426
Oligopeptides: 519
acetyl-arginyl-glutamyl-arginine: 1
Experts
1.
Mileusnic, Radmila
: 1 article (08/2011)
2.
Rose, Steven P R
: 1 article (08/2011)
Related Diseases
1.
Amnesia (Dissociative Amnesia)
08/01/2011 - "
Behavioural studies of the effects of Ac-rER on memory retention confirmed that the effect of Ac-rER is mediated via CRMP2, as anti-CRMP2 antibodies if injected intracranially 30 min pre-training, induced amnesia for the passive avoidance task.
"
2.
Memory Disorders (Memory Loss)
08/01/2011 - "
However, Ac-rER, if injected prior to the anti-CRMP2, rescues the memory deficits induced by anti-CRMP2 antibodies.
"
3.
Alzheimer Disease (Alzheimer's Disease)
08/01/2011 - "
As CRMP2 is placed at the junction of many different cellular processes during brain development and in adult neuronal plasticity as well as being implicated in Alzheimer's disease, this strengthens the claim that Ac-rER may be a potential therapeutic agent in Alzheimer's disease, although its precise mode of action remains to be elucidated.
"
Related Drugs and Biologics
1.
Antibodies