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bisnaphthalimidopropyldiaaminooctane

an antineoplastic agent; structure in first source

Also Known As:

BNIPDaoct

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Tavares, Joana: 3 articles (12/2012 - 01/2007)
2.	Cordeiro-da-Silva, Anabela: 2 articles (12/2012 - 06/2012)
3.	Lin, Paul Kong Thoo: 2 articles (12/2012 - 06/2012)
4.	Ouaissi, Ali: 2 articles (12/2012 - 06/2012)
5.	Costa Lima, Sofia A: 1 article (12/2012)
6.	Resende, Mariana: 1 article (12/2012)
7.	Silvestre, Ricardo: 1 article (12/2012)
8.	Roy, Nilanjan: 1 article (06/2012)
9.	Silva, Ana Marta: 1 article (06/2012)
10.	Bestwick, Charles S: 1 article (01/2007)

Related Diseases

1.	Visceral Leishmaniasis (Kala Azar) 12/01/2012 - "Characterization and evaluation of BNIPDaoct-loaded PLGA nanoparticles for visceral leishmaniasis: in vitro and in vivo studies." 12/01/2012 - "To overcome the limitation of bisnaphthalimidopropyldiaaminooctane (BNIPDaoct) low physiological solubility and potentially increase its efficiency against visceral leishmaniasis (VL), a delivery system based on poly(d,l-lactide-co-glycolide) (PLGA) nanoparticles was developed. "
2.	Leishmaniasis 06/01/2012 - "Moreover, no indications of hematological toxicity were detected as evaluated by the hemoglobin, hematocrit, white and red blood cell counts, hence making BNIPDaoct a potential therapeutic agent against leishmaniasis." 06/01/2012 - "Indeed, at a dose of 1mg/kg, BNIPDaoct was more effective to treat leishmaniasis in a short course treatment (3 or 6 drug administrations) than the standard amphotericin B. "
3.	Colonic Neoplasms (Colon Cancer) 01/01/2007 - "Bisnaphthalimidopropyl derivatives (BNIPSpd, BNIPDaoct, BNIPDanon, BNIPDadec, BNIPDpta and BNIPDeta) were synthesised in yields ranging from 50% to 70% and their cytotoxicity against colon cancer cells (Caco-2) and the parasite Leishmania infantum determined using the MTT assay. "

Related Drugs and Biologics

1.	bisnaphthalimidopropyldiaaminooctane
2.	Hemoglobins (Hemoglobin)
3.	Amphotericin B (Amphotericin)
4.	Polylactic Acid-Polyglycolic Acid Copolymer
5.	bisnaphthalimidopropylspermidine