gegenqinlian

Consists of 4 Chinese medicinal herbs: Radix Puerariae (Gegen in Chinese), Radix Scutellariae (Huangqin in Chinese), Rhizoma Coptidis (Huanglian in Chinese), and Radix Glycyrrhizae (Gancao in Chinese).

Also Known As:

Networked: 97 relevant articles (14 outcomes, 25 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Zhao, Linhua: 3 articles (03/2022 - 12/2020)
2.	Liu, Ting: 3 articles (11/2021 - 03/2018)
3.	Yu, Zhiguo: 3 articles (11/2021 - 03/2018)
4.	Zhao, Yunli: 3 articles (11/2021 - 03/2018)
5.	Tu, Jun: 3 articles (09/2021 - 12/2017)
6.	Li, Ruiyan: 3 articles (04/2021 - 09/2016)
7.	Wu, Xiaojun: 3 articles (04/2021 - 09/2016)
8.	Zhang, Yubin: 3 articles (04/2021 - 09/2016)
9.	Zhao, Yaxing: 3 articles (04/2021 - 09/2016)
10.	Li, Jun-Xiang: 3 articles (01/2018 - 01/2015)

Related Diseases

1.	Ulcerative Colitis 12/01/2019 - "Efficacy of herbal medicine (Gegen Qinlian Decoction) on ulcerative colitis: A systematic review of randomized controlled trials." 04/01/2021 - "Gegen Qinlian decoction relieved DSS-induced ulcerative colitis in mice by modulating Th17/Treg cell homeostasis via suppressing IL-6/JAK2/STAT3 signaling." 12/01/2019 - "This systematic review aims to evaluate the efficacy of Gegen Qinlian Decoction (GQD) for ulcerative colitis (UC). " 02/01/2022 - "This study established a mouse model of ulcerative colitis and explored the serum transitional components of Gegen Qinlian Decoction by UHPLC-Q-Orbitrap-MS. Based on the exact relative molecular weight and MS/MS spectrum, 55 prototype components and 59 metabolites were identified from the model group, while 18 prototype components and 35 metabolites from the control group. " 02/01/2022 - "[Study on serum pharmacodynamic material basis of Gegen Qinlian Decoction in treatment of ulcerative colitis based on UHPLC-Q-Orbitrap-MS]."
2.	Type 2 Diabetes Mellitus (MODY) 01/01/2022 - "Gegen Qinlian Decoction (GQD) has achieved good results in the treatment of type 2 diabetes (T2D). " 01/01/2020 - "Herbal Formula Gegen-Qinlian Decoction for Type 2 Diabetes Mellitus: A Meta-Analysis of Randomized Controlled Trials." 01/01/2022 - "Exploring Anti-Type 2 Diabetes Mellitus Mechanism of Gegen Qinlian Decoction by Network Pharmacology and Experimental Validation." 01/01/2020 - "Herbal formula Gegen-Qinlian Decoction (GQD) has been widely used in China for the treatment of type 2 diabetes mellitus (T2DM), but its efficacy and safety are unclear. " 01/01/2022 - "Gegen Qinlian Decoction (GGQL) has been employed to treat type 2 diabetes mellitus (T2DM) in the clinical practice of traditional Chinese medicine. "
3.	Colitis 03/01/2023 - "Modified Gegen Qinlian decoction ameliorates DSS-induced chronic colitis in mice by restoring the intestinal mucus barrier and inhibiting the activation of γδT17 cells." 01/01/2021 - "Modified Gegen Qinlian Decoction Regulates Treg/Th17 Balance to Ameliorate DSS-Induced Acute Experimental Colitis in Mice by Altering the Gut Microbiota." 09/15/2016 - "Gegen Qinlian decoction (GQ), a Chinese medicinal herb decoction, has been widely used as efficient medicine for the treatment of acute colitis in clinics, but underlying molecular mechanisms have not been fully clarified. " 09/01/2005 - "The effects of different compositions of Gegenqinlian decoction on the indexes of colitis and the bacterial count of Shigella in the colon content and colon tissue were investigated by orthogonal design. " 01/01/2022 - "Gegen Qinlian Decoction Alleviates Experimental Colitis and Concurrent Lung Inflammation by Inhibiting the Recruitment of Inflammatory Myeloid Cells and Restoring Microbial Balance."
4.	Insulin Resistance 11/13/2019 - "Gegen Qinlian Decoction Ameliorates Hepatic Insulin Resistance by Silent Information Regulator1 (SIRT1)-Dependent Deacetylation of Forkhead Box O1 (FOXO1)." 01/10/2021 - "Identification of potential bioactive compounds and mechanisms of GegenQinlian decoction on improving insulin resistance in adipose, liver, and muscle tissue by integrating system pharmacology and bioinformatics analysis." 12/01/2017 - "To investigate the effects of Gegen Qinlian decoction(GQD) in improving adipocytic insulin resistance(IR) and explore its related molecular mechanism. " 12/01/2017 - "[Gegen Qinlian decoction activates PPARγ to ameliorate adipocytic insulin resistance in diabetic SD rats and IR-3T3-L1 adipocytes]." 09/01/2021 - "[Effects and mechanisms of Supplemented Gegen Qinlian Decoction Formula against podocyte pyroptosis and insulin resistance in model rats with diabetic kidney disease]."
5.	Non-alcoholic Fatty Liver Disease 11/01/2017 - "The present study aimed to explore the mechanism of action of Gegen Qinlian decoction (GGQLD) in experimental non-alcoholic fatty liver disease (NAFLD). " 01/01/2021 - "Gegen Qinlian Decoction (GQD), a classic Chinese herbal formula, has been widely used in Chinese clinic for centuries and is well defined in treating nonalcoholic fatty liver disease (NAFLD). " 01/01/2015 - "This paper is to explore the effect and mechanism of Gegenqinlian decoction on experimental nonalcoholic fatty liver disease (NAFLD) in vivo and in vitro. " 01/01/2015 - "Intervening TNF-α via PPARγ with Gegenqinlian Decoction in Experimental Nonalcoholic Fatty Liver Disease." 01/01/2021 - "Gegen Qinlian Decoction Ameliorates Nonalcoholic Fatty Liver Disease in Rats via Oxidative Stress, Inflammation, and the NLRP3 Signal Axis."

Related Drugs and Biologics

1.	Peroxisome Proliferator-Activated Receptors (PPAR)
2.	Cytokines
3.	Berberine
4.	Enzymes
5.	Therapeutic Uses
6.	Messenger RNA (mRNA)
7.	Biomarkers (Surrogate Marker)
8.	Polysaccharides (Glycans)
9.	Glucose (Dextrose)
10.	Blood Glucose (Blood Sugar)

Related Therapies and Procedures

1.	Chinese Traditional Medicine (Traditional Chinese Medicine)
2.	Oral Administration
3.	Cyclotrons
4.	Traditional Medicine (Folk Remedies)
5.	Enema (Enemas)