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6-hydroxybuspirone
active metabolite of buspirone
Networked:
1
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Spiro Compounds: 2
Buspirone: 740
6-hydroxybuspirone: 1
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyrimidines: 510
Buspirone: 740
6-hydroxybuspirone: 1
Piperazines: 26
Buspirone: 740
6-hydroxybuspirone: 1
Polycyclic Compounds: 6
Spiro Compounds: 2
Buspirone: 740
6-hydroxybuspirone: 1
Related Diseases
1.
Hepatocellular Carcinoma (Hepatoma)
08/01/2023 - "
In this study, we examined the interaction of buspirone and its major metabolites 1-(2-pyrimidinyl)piperazine (1-PP) and 6-hydroxybuspirone (6'-OH-Bu) with hOCTs using human hepatocellular carcinoma (HepG2), human colorectal adenocarcinoma (Caco-2) cells, and S2 cells expressing OCT1 (S2hOCT1), 2 (S2hOCT2), or 3 (S2hOCT3).
"
2.
Adenocarcinoma
08/01/2023 - "
In this study, we examined the interaction of buspirone and its major metabolites 1-(2-pyrimidinyl)piperazine (1-PP) and 6-hydroxybuspirone (6'-OH-Bu) with hOCTs using human hepatocellular carcinoma (HepG2), human colorectal adenocarcinoma (Caco-2) cells, and S2 cells expressing OCT1 (S2hOCT1), 2 (S2hOCT2), or 3 (S2hOCT3).
"
Related Drugs and Biologics
1.
Buspirone (Buspar)
2.
1-(2-pyrimidinyl)piperazine