lactiflorin

isolated from roots of Paeonia sinjiangensis

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Atherosclerosis 03/01/2023 - "Through PPI network, we found that the top three proteins were RAC-alpha serine/threonine protein kinase (AKT1), vascular endothelial growth factor A (VEGFA), and transcription factor Jun (JUN), and their corresponding components were kaempferol, paeoniflorin, lactiflorin, paeoniflorgenone, etc. The results of enrichment analysis suggested that WP treatment for LN mainly involves in signaling pathways in cancer, lipid and atherosclerosis, advanced glycation end product (AGE)-receptor of AGE (RAGE) pathways, C-type lectin receptor and nuclear factor (NF)-kappa B signaling pathways. "
2.	Uremia 11/15/2022 - "Zhen-Wu decoction and lactiflorin, an ingredient predicted by in silico modelling, alleviate uremia induced cardiac endothelial injury via Nrf2 activation."
3.	Neoplasms (Cancer) 03/01/2023 - "Through PPI network, we found that the top three proteins were RAC-alpha serine/threonine protein kinase (AKT1), vascular endothelial growth factor A (VEGFA), and transcription factor Jun (JUN), and their corresponding components were kaempferol, paeoniflorin, lactiflorin, paeoniflorgenone, etc. The results of enrichment analysis suggested that WP treatment for LN mainly involves in signaling pathways in cancer, lipid and atherosclerosis, advanced glycation end product (AGE)-receptor of AGE (RAGE) pathways, C-type lectin receptor and nuclear factor (NF)-kappa B signaling pathways. "

1.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
2.	C-Type Lectins (C-Type Lectin)
3.	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)
4.	Advanced Glycation End Products
5.	NF-kappa B (NF-kB)
6.	Transcription Factors (Transcription Factor)
7.	Proteins (Proteins, Gene)
8.	Lipids
9.	Receptor for Advanced Glycation End Products
10.	peoniflorin