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ilexsaponin A1

extract from the leaves of the plant

Networked: 4 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycosides: 2119
  - Saponins: 2867
    - ilexsaponin A1: 4

Experts

1.	Wu, Xia: 2 articles (01/2021 - 10/2019)
2.	Xiao, Meng: 2 articles (01/2021 - 10/2019)
3.	Bao, Yuqing: 1 article (10/2021)
4.	Jin, Xiaoliang: 1 article (10/2021)
5.	Kang, An: 1 article (10/2021)
6.	Lv, Tingmei: 1 article (10/2021)
7.	Miao, Peng: 1 article (10/2021)
8.	Wu, Liang: 1 article (10/2021)
9.	Zhou, Zhu: 1 article (10/2021)
10.	Chen, Xiao-Qing: 1 article (01/2021)

Related Diseases

1.	Non-alcoholic Fatty Liver Disease 01/01/2021 - "We aimed to investigate the effect of ilexsaponin A1 (IsA), a major bioactive ingredient of Ilex, on high-fat diet (HFD)-induced NAFLD in mice with a focus on BA homeostasis. " 01/01/2021 - "Ilexsaponin A1 Ameliorates Diet-Induced Nonalcoholic Fatty Liver Disease by Regulating Bile Acid Metabolism in Mice." 10/01/2019 - "The combination of Ilexhainanoside D and ilexsaponin A1 reduces liver inflammation and improves intestinal barrier function in mice with high-fat diet-induced non-alcoholic fatty liver disease." 10/01/2019 - "extract was proved to have anti-inflammation effect on NAFLD, and Ilexhainanoside D (IhD) and ilexsaponin A1 (IsA) were the main triterpenoid saponins extracted from it. "
2.	Cardiovascular Diseases (Cardiovascular Disease) 12/01/2017 - "The findings suggest that Ilexsaponin A1 and probably I. pubescens, a major source of Ilexsaponin A1, could be developed as a potential therapeutic agent for preventing or treating cardiovascular diseases and/or other diseases related to vascular insufficiency." 10/01/2021 - "As a triterpene saponin, ilexsaponin A1 is one of the most abundant, representative and active components in plants of Ilex pubescens, used in the treatment of cardiovascular diseases. "
3.	Inflammation (Inflammations) 10/01/2019 - "The combination of Ilexhainanoside D and ilexsaponin A1 reduces liver inflammation and improves intestinal barrier function in mice with high-fat diet-induced non-alcoholic fatty liver disease." 10/01/2019 - "extract was proved to have anti-inflammation effect on NAFLD, and Ilexhainanoside D (IhD) and ilexsaponin A1 (IsA) were the main triterpenoid saponins extracted from it. "

Related Drugs and Biologics

1.	Bile Acids and Salts (Bile Acids)
2.	Triterpenes
3.	Saponins
4.	Ilexhainanoside D