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ligustroflavone

an apigenin triglycoside from the leaves of Ligustrum vulgare; structure in first source

Also Known As:

apigenin-7-O-beta-(2'',6''-di-alpha-rhamnopyranosyl)-glucopyranoside

Networked: 4 relevant articles (3 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Cao, Wei: 1 article (03/2021)
2.	Feng, Ying-Da: 1 article (03/2021)
3.	Kang, Rong: 1 article (03/2021)
4.	Li, Chen: 1 article (03/2021)
5.	Li, Xiao-Qiang: 1 article (03/2021)
6.	Li, Ze-Zhi: 1 article (03/2021)
7.	Sun, Yang: 1 article (03/2021)
8.	Tian, Wen: 1 article (03/2021)
9.	Zhang, Hui-Nan: 1 article (03/2021)
10.	Ding, Fan: 1 article (01/2019)

Related Diseases

1.	Osteoporosis 01/01/2019 - "This study aimed to explore the potency of ligustroflavone as a CaSR antagonist and its protective effects against diabetic osteoporosis in mice. " 01/01/2019 - "Protective Effects of Ligustroflavone, an Active Compound from Ligustrum lucidum, on Diabetes-Induced Osteoporosis in Mice: A Potential Candidate as Calcium-Sensing Receptor Antagonist." 01/01/2019 - "Taken together, ligustroflavone could transiently increase PTH level and regulate calcium metabolism as well as prevent osteoporosis in diabetic mice, suggesting that ligustroflavone might be an effective antagonist on CaSR."
2.	Liver Cirrhosis (Hepatic Cirrhosis) 03/01/2021 - "Ligustroflavone ameliorates CCl4-induced liver fibrosis through down-regulating the TGF-β/Smad signaling pathway."
3.	Ischemia 01/01/2019 - "Administration of ligustroflavone (30 mg/kg, i.g.) 15 min before ischemia evidently improved neurological function, reduced infarct volume, and decreased the levels of necroptosis-associated proteins except the RIPK1. "
4.	Infarction (Infarctions) 01/01/2019 - "Administration of ligustroflavone (30 mg/kg, i.g.) 15 min before ischemia evidently improved neurological function, reduced infarct volume, and decreased the levels of necroptosis-associated proteins except the RIPK1. "
5.	Stroke (Strokes) 01/01/2019 - "This study aims to explore the effect of ligustroflavone on ischemic brain injury in stroke rat and the underlying mechanisms. "

Related Drugs and Biologics

1.	Calcium-Sensing Receptors
2.	Proteins (Proteins, Gene)
3.	Inflammasomes
4.	Complement System Proteins (Complement)
5.	Calcium