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N1445

Also Known As:

N 1445; Z-Asp-CH2-cytochalasin B

Networked: 5 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 207
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 205
      - Cytochalasins: 40
        N1445: 5
Biological Factors: 2560
- Biological Toxins: 20
  - Mycotoxins: 1799
    - Cytochalasins: 40
      - N1445: 5

Experts

1.	Biel, Frances M: 1 article (02/2024)
2.	Cartwright, Natalie: 1 article (02/2024)
3.	Cook, Nicole: 1 article (02/2024)
4.	Gordon, Michelle: 1 article (02/2024)
5.	Hoopes, Megan: 1 article (02/2024)
6.	Sills, Marion: 1 article (02/2024)
7.	Allem, Jon-Patrick: 1 article (02/2018)
8.	Baezconde-Garbanati, Lourdes: 1 article (02/2018)
9.	Escobedo, Patricia: 1 article (02/2018)
10.	Unger, Jennifer B: 1 article (02/2018)

Related Diseases

1.	Neoplasms (Cancer) 09/01/1999 - "Like the F-actin cross-linking drug MKT-077, the F-actin capping drug CK may be useful for the treatment of Ras-associated cancers if it is combined with the ICE inhibitor N1445, which abolishes the side effect of CK. " 09/01/1999 - "Treatment of Ras-induced cancers by the F-actin cappers tensin and chaetoglobosin K, in combination with the caspase-1 inhibitor N1445."
2.	Binge Drinking 02/01/2018 - "Among participants (n=1445, mean age=23, 60% female), 21% reported past month cigarette use, 18% reported past month alternative tobacco product (ATP) use, 25% reported past month marijuana use, 44% reported past month binge drinking, and 7% reported past month hard drug use. "
3.	Substance-Related Disorders (Drug Abuse) 02/05/2024 - "Among patients reporting exposure, 52.7% (n=1669) were male, 38.8% (n=1229) were Black, 45.7% (n=1445) had posttraumatic stress disorder, 37.5% (n=1186) had a substance abuse disorder (other than nicotine), and 11.7% (n=371) had hypertension. "
4.	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 02/05/2024 - "Among patients reporting exposure, 52.7% (n=1669) were male, 38.8% (n=1229) were Black, 45.7% (n=1445) had posttraumatic stress disorder, 37.5% (n=1186) had a substance abuse disorder (other than nicotine), and 11.7% (n=371) had hypertension. "
5.	Insulin Resistance 04/01/2017 - "A total of 1732 young adults were enrolled and allocated into groups with (n=287) and without (n=1445) insulin resistance. "

Related Drugs and Biologics

1.	Ice
2.	Actins (F Actin)
3.	MKT 077
4.	Cytochrome P-450 CYP11B2 (CYP11B2)
5.	Nicotine
6.	Adenosine Triphosphate (ATP)
7.	Tensins
8.	interleukin-1beta-converting enzyme inhibitor
9.	chaetoglobosins