picroside I

11/01/2020 - "Moreover, this study revealed how picroside I could protect against TAA-induced liver fibrosis in mice. "

01/01/2021 - "In our study, we used picroside I and II as the lead compounds to generate derivatives by reactions with Boc-valine or Boc-proline, which underwent dehydration and condensation with the hydroxyl groups in the lead compounds in the presence of coupling reagent N,N'-dicyclohexylcarbodiimide. "

11/01/2020 - "Results indicated that picroside I can serve as a candidate drug for hepatic fibrosis."
11/01/2020 - "This work aimed to explore the mechanism underlying the hepatoprotective effect of picroside I against hepatic fibrosis. "
11/01/2020 - "Picroside I altered metabolomic profiles, including energy, lipid, and glutathione (GSH) metabolism, in ice with fibrosis. "
11/01/2020 - "Protective effect of picroside I against hepatic fibrosis in mice via sphingolipid metabolism, bile acid biosynthesis, and PPAR signaling pathway."
11/01/2020 - "Data showed that picroside I could decrease the serum levels of alanine transaminase (ALT), aspartate transaminase (AST), collagen type IV (CIV), N-terminal peptide of type III procollagen (PIIINP), laminin (LN), and hyaluronic acid (HA) and reduced fibrosis area. "