thaliporphine

from plant Neolitsea konishii K; potent agonist of vascular smooth muscle contractions in the presence of calcium; RN given refers to parent cpd (S)-isomer; RN for cpd without isomeric designation not avail 5/93

Also Known As:

thaliporphine hydrochloride

Networked: 8 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Benzylisoquinolines: 151
    - Aporphines: 10
      - thaliporphine: 8
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Isoquinolines: 34
      - Benzylisoquinolines: 151
        Aporphines: 10
        thaliporphine: 8
  - 4 or More Rings Heterocyclic Compounds
    - Aporphines: 10
      - thaliporphine: 8

Experts

1.	Lee, Shoei-Sheng: 4 articles (12/2010 - 01/2005)
2.	Su, Ming-Jai: 4 articles (12/2010 - 01/2005)
3.	Alibolandi, Zahra: 1 article (04/2022)
4.	Aschner, Michael: 1 article (04/2022)
5.	Dadgostar, Ehsan: 1 article (04/2022)
6.	Mirzaei, Hamed: 1 article (04/2022)
7.	Naderi Taheri, Mojtaba: 1 article (04/2022)
8.	Nazemi, Sina: 1 article (04/2022)
9.	Nikmanzar, Shahin: 1 article (04/2022)
10.	Rahimi, Shiva: 1 article (04/2022)

Related Diseases

1.	Myocardial Ischemia (Ischemic Heart Diseases) 01/01/2005 - "This study evaluated whether thaliporphine administered at a certain period after myocardial ischemia conferred the same cardioprotection and assessed its possible new mechanism. "
2.	Shock 12/01/2010 - "Thaliporphine was found to ameliorate endotoxin-induced circulatory failure and mortality in rodents. " 01/01/2005 - "In conclusion, our results suggest that thaliporphine could be a novel agent for attenuating endotoxin-induced circulatory failure and multiple organ injury and may increase the survival rate. "
3.	Necrosis 01/01/2005 - "Endotoxaemia for 240 min resulted in a bell-shaped time course for the change of serum tumour necrosis factor-alpha (TNF-alpha) level with a peak at 60 min. Pretreatment of LPS-treated rats with 1 mg/kg thaliporphine significantly reduced the serum TNF-alpha level at 60 min. In addition, LPS caused a biphasic change in blood glucose and thaliporphine attenuated the late-phase decrease in blood glucose. " 10/01/1994 - "Thaliporphine (0.1-100 microM) dose-dependently inhibited nitrite accumulation in macrophages stimulated by interleukin-1 beta (IL-1 beta) whereas nitrite formation induced by tumour necrosis factor alpha was not inhibited. "
4.	Acute Lung Injury 01/01/2015 - "Thaliporphine derivative improves acute lung injury after traumatic brain injury."
5.	Sepsis (Septicemia) 01/01/2012 - "Thaliporphine could protect sepsis-associated myocardial dysfunction in both preload-dependent and -independent ways. "

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5.	Adenosine A2A Receptor (Adenosine A2A Receptors)
6.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
7.	Nerve Growth Factor (NGF)
8.	Poloxamer (Poloxamer 407)
9.	Tacrolimus (Prograf)
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Related Therapies and Procedures

1.	Therapeutics