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AL 3152
structure given in first source; derivative of imirestat
Also Known As:
2,7-difluoro-4-methoxyspiro-(9H-fluorene-9,4'-imidazolidine)-2',5'-dione; AL-3152; ALO 3152; ALO-3152; Spiro(9H-fluorene-9,4'-imidazolidine)-2',5'-dione, 2,7-difluoro-4-methoxy-
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Polycyclic Aromatic Hydrocarbons: 2020
Fluorenes: 7
AL 3152: 1
Polycyclic Compounds: 6
Polycyclic Aromatic Hydrocarbons: 2020
Fluorenes: 7
AL 3152: 1
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Imidazoles: 150
Imidazolidines: 39
Hydantoins: 306
AL 3152: 1
Related Diseases
1.
Galactosemias (Galactosemia)
05/01/1997 - "
Although the microangiopathies were ameliorated by AL-3152 treatment from the onset (PRV), intervention after 6 months of galactosemia with either galactose withdrawal (GWD) or addition of inhibitor (INT) showed amelioration in only some parameters at 18 months and no statistically significant benefit at the 24-month endpoint.
"
2.
Diabetic Retinopathy (Retinopathy, Diabetic)
05/01/1997 - "
Amelioration of galactose-induced retinal microangiopathies with AL-3152 in the prevention group suggests an efficacious application of aldose reductase inhibitors in treating diabetic retinopathy, provided treatment can begin soon after the onset of diabetes.
"
Related Drugs and Biologics
1.
Retinaldehyde (Retinal)
2.
Galactose (Galactopyranose)
3.
Aldehyde Reductase (Aldose Reductase)