FKBP-13

amino acid sequence of human FKBP-13 given in first source; a membrane-associated human FK506- & rampamycin-binding protein; see also record for FK 506 binding protein

Also Known As:

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Abed, Soumeya: 1 article (01/2021)
2.	Ask, Kjetil: 1 article (01/2021)
3.	Ayaub, Ehab A: 1 article (01/2021)
4.	Ayoub, Anmar: 1 article (01/2021)
5.	Bellaye, Pierre-Simon: 1 article (01/2021)
6.	Cutz, Jean-Claude: 1 article (01/2021)
7.	Dvorkin-Gheva, Anna: 1 article (01/2021)
8.	Hambly, Nathan: 1 article (01/2021)
9.	Kato, Jiro: 1 article (01/2021)
10.	Kolb, Martin R J: 1 article (01/2021)

Related Diseases

1.	Plasmacytoma 01/01/2017 - "FKBP13 overexpression caused a significant reduction in secreted IgA in plasmacytoma cells, and FKBP13 knockdown exerted an opposite effect. " 01/01/2017 - "Here, we found marked overexpression of FK506-binding protein 13 (FKBP13) in long-lived PCs from autoimmune mice and investigated its function using a plasmacytoma cell line secreting IgA. "
2.	Fibrosis (Cirrhosis) 01/01/2021 - "FKBP13: A New Player on the Block in Endoplasmic Reticulum Stress and Lung Fibrosis." 01/01/2021 - "FKBP13-/- mice showed increased infiltration of inflammatory cells and cytokines at Day 7, increased lung elastance and fibrosis at Day 21, and impaired resolution of fibrosis at Day 50. " 01/01/2021 - "Our findings suggest that FKBP13 is a potential biomarker for severity of interstitial lung diseases and that it has a biologically relevant role in protecting mice against bleomycin-induced injury, inflammation, and fibrosis."
3.	Idiopathic Pulmonary Fibrosis 01/01/2021 - "FKBP13 expression was found to be elevated in the fibrotic regions of idiopathic pulmonary fibrosis lung tissues and correlated with declining forced vital capacity and dyspnea severity. " 01/01/2021 - "We first characterized the gene and protein expression of FKBP13 in lung biopsy specimens from 24 patients with idiopathic pulmonary fibrosis and 17 control subjects. "
4.	Interstitial Lung Diseases (Interstitial Lung Disease) 01/01/2021 - "FKBP13 expression was also increased in lung biopsy specimens of patients with hypersensitivity pneumonitis, rheumatoid arthritis, and sarcoidosis-associated interstitial lung disease. " 01/01/2021 - "Our findings suggest that FKBP13 is a potential biomarker for severity of interstitial lung diseases and that it has a biologically relevant role in protecting mice against bleomycin-induced injury, inflammation, and fibrosis."
5.	Sarcoidosis (Schaumann Disease) 01/01/2021 - "FKBP13 expression was also increased in lung biopsy specimens of patients with hypersensitivity pneumonitis, rheumatoid arthritis, and sarcoidosis-associated interstitial lung disease. "

Related Drugs and Biologics

1.	Immunoglobulin A (IgA)
2.	Tacrolimus Binding Proteins (FKBP)
3.	Molecular Chaperones (Chaperone, Molecular)
4.	Cytokines
5.	Biomarkers (Surrogate Marker)
6.	Proteins (Proteins, Gene)
7.	Bleomycin (Blenoxane)