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enhancer-binding protein NF-E4
MW 65 kDa; trans-acting factor that confers definitive erythroid stage-specific transcriptional activation to the adult beta-globin gene
Also Known As:
NF-E4; nuclear factor-erythroid 4; trans-acting factor NF-E4
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Proteins: 484843
Transcription Factors: 38804
enhancer-binding protein NF-E4: 1
Experts
1.
Cerruti, L
: 1 article (10/2000)
2.
Clouston, D R
: 1 article (10/2000)
3.
Cunningham, J M
: 1 article (10/2000)
4.
Jane, S M
: 1 article (10/2000)
5.
Wang, X
: 1 article (10/2000)
6.
Zhou, W
: 1 article (10/2000)
Related Diseases
1.
Hemoglobinopathies
10/01/2000 - "
Enforced expression of NF-E4 in K562 cells and primary erythroid progenitors induces endogenous fetal globin gene expression, suggesting a possible strategy for therapeutic intervention in the hemoglobinopathies.
"
Related Drugs and Biologics
1.
Globins