VAB-6 regimen

chemotherapy protocol consisting of the above cpds; used in treatment of patients with germ cell tumors

Networked: 4 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Therapy Context: Research Results

Therapeutics: 1158551
- Drug Therapy: 293145
  - Combination Drug Therapy: 12066
    - Antineoplastic Combined Chemotherapy Protocols: 35
      - VAB-6 regimen: 4
  - Antineoplastic Protocols: 55
    - Antineoplastic Combined Chemotherapy Protocols: 35
      - VAB-6 regimen: 4
- Clinical Protocols
  - Antineoplastic Protocols: 55
    - Antineoplastic Combined Chemotherapy Protocols: 35
      - VAB-6 regimen: 4
Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycopeptides: 1928
    - Bleomycin: 9833
      - VAB-6 regimen: 4
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Glycopeptides: 1928
    - Bleomycin: 9833
      - VAB-6 regimen: 4
  - Cyclic Peptides: 530
    - Dactinomycin: 2073
      - VAB-6 regimen: 4
Inorganic Chemicals: 9
Organic Chemicals: 133
- Hydrocarbons: 1713
  - Halogenated Hydrocarbons: 42
    - Mustard Compounds: 3
      - Nitrogen Mustard Compounds: 2
        Phosphoramide Mustards: 5
        Cyclophosphamide: 25473
        VAB-6 regimen: 4
- Organophosphorus Compounds: 300
  - Phosphoramides: 8
    - Phosphoramide Mustards: 5
      - Cyclophosphamide: 25473
        VAB-6 regimen: 4
Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Indole Alkaloids: 200
    - Secologanin Tryptamine Alkaloids: 81
      - Vinca Alkaloids: 463
        Vinblastine: 3373
        VAB-6 regimen: 4
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - Indole Alkaloids: 200
        Secologanin Tryptamine Alkaloids: 81
        Vinca Alkaloids: 463
        Vinblastine: 3373
        VAB-6 regimen: 4
    - Indolizines: 3
      - Indolizidines: 2
        Indole Alkaloids: 200
        Secologanin Tryptamine Alkaloids: 81
        Vinca Alkaloids: 463
        Vinblastine: 3373
        VAB-6 regimen: 4
  - 3-Ring Heterocyclic Compounds
    - Dactinomycin: 2073
      - VAB-6 regimen: 4
Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - Dactinomycin: 2073
      - VAB-6 regimen: 4

Related Diseases

1.	Seminoma 06/01/1984 - "In an attempt to improve complete remission rates, seven patients with Stage III or bulky Stage II pure seminoma of the testis were treated with the VAB-6 regimen. " 06/01/1984 - "The VAB-6 regimen is effective in the treatment of advanced metastatic seminoma." 06/01/1984 - "The VAB-6 regimen in the treatment of metastatic seminoma."
2.	Endodermal Sinus Tumor (Endodermal Sinus Tumors) 01/01/1995 - "[A case report of a 6-year-old boy with intracranial yolk sac tumor treated by VAB-6 regimen]."
3.	Germ Cell and Embryonal Neoplasms (Germ Cell Tumor) 01/01/1983 - "Twenty-four patients with resected Stage II-B nonseminomatous germ cell tumors of the testis received adjuvant chemotherapy with the modified VAB-6 regimen for one year. "
4.	Neoplasms (Cancer) 01/01/1990 - "In cases of minimal and moderate advancement (group 1), induction chemotherapy included three cycles of VAB-6 regimen (vinblastine, actinomycin D, bleomycetin, cyclophosphamide plus 120 mg/m2 platidiam) whereas cases of advanced tumor (group 2) received six such cycles; two of them used 150 mg/m2 platidiam dropwise in a 3% sodium chloride solution. "

Related Drugs and Biologics

1.	Vinblastine (Vinblastine Sulfate)
2.	Solutions
3.	Sodium Chloride
4.	Dactinomycin (Actinomycin)
5.	Cyclophosphamide (Cytoxan)
6.	Cisplatin (Platino)
7.	bleomycetin

Related Therapies and Procedures

1.	Induction Chemotherapy
2.	Adjuvant Chemotherapy