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1- methyl- 4- (1- methylpyrrol- 2- yl)- 4- piperidinol
structure given in first source
Also Known As:
1-MMPP; 4-Piperidinol, 1-methyl-4-(1-methyl-1H-pyrrol-2-yl)-
Networked:
2
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Piperidines: 17
1-methyl-4-(1-methylpyrrol-2-yl)-4-piperidinol: 2
Related Diseases
1.
Dehydration (Water Stress)
01/01/1990 - "
Studies of the in vitro oxidation of 1-methyl-4-(1-methylpyrrol-2-yl)-4-piperidinol and its dehydration product 1,2,3,6-tetrahydro-1-methyl-4-(methylpyrrol-2-yl) pyridine by human monoamine oxidases A and B.
"
01/01/1990 - "
The ability of highly purified preparations of human monoamine oxidase A and B (MAO A and B) to utilize 1-methyl-4-(1-methylpyrrol-2-yl)-4-piperidinol (MMPP) and its dehydration product 1,2,3,6-tetrahydro-1-methyl-4-(methylpyrrol-2-yl) pyridine (TMMP) as substrates was investigated.
"
2.
Hypokinesia (Bradykinesia)
03/19/1986 - "
A neurologic deficit characterized by hypokinesia, postural flexion, and to a lesser extent, rigidity, tremor and myoclonus, has been observed in cynomolgus monkeys following administration of 1-methyl-4-(1-methylpyrrol-2-yl)-4-piperidinol (MMPP), a novel 4-substituted piperidine.
"
3.
Tremor (Tremors)
03/19/1986 - "
A neurologic deficit characterized by hypokinesia, postural flexion, and to a lesser extent, rigidity, tremor and myoclonus, has been observed in cynomolgus monkeys following administration of 1-methyl-4-(1-methylpyrrol-2-yl)-4-piperidinol (MMPP), a novel 4-substituted piperidine.
"
4.
Neurologic Manifestations (Neurological Manifestations)
03/19/1986 - "
A neurologic deficit characterized by hypokinesia, postural flexion, and to a lesser extent, rigidity, tremor and myoclonus, has been observed in cynomolgus monkeys following administration of 1-methyl-4-(1-methylpyrrol-2-yl)-4-piperidinol (MMPP), a novel 4-substituted piperidine.
"
5.
Myoclonus (Nocturnal Myoclonus)
03/19/1986 - "
A neurologic deficit characterized by hypokinesia, postural flexion, and to a lesser extent, rigidity, tremor and myoclonus, has been observed in cynomolgus monkeys following administration of 1-methyl-4-(1-methylpyrrol-2-yl)-4-piperidinol (MMPP), a novel 4-substituted piperidine.
"
Related Drugs and Biologics
1.
Oxidoreductases (Dehydrogenase)
2.
pyridine
3.
magnesium monoperoxyphthalate
4.
Monoamine Oxidase (MAO)
5.
human monoamine oxidase A
6.
1- methyl- 4- (methylpyrrol- 2- yl)- 1,2,3,6- tetrahydropyridine
7.
piperidine