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Azure A

RN given refers to chloride

Also Known As:

7-(dimethylamino)-3-imino-3H-phenothiazine hydrochloride; Azure A bromide; Phenothiazin-5-ium, 3-amino-7-(dimethylamino)-, chloride

Networked: 13 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 140
- Sulfur Compounds: 283
  - Phenothiazines: 510
    - Azure Stains: 215
      - Azure A: 13
Heterocyclic Compounds: 207
- Fused-Ring Heterocyclic Compounds
  - 3-Ring Heterocyclic Compounds
    - Phenothiazines: 510
      - Azure Stains: 215
        Azure A: 13

Experts

1.	Baker, C A: 2 articles (09/2012 - 02/2007)
2.	Arias Barquet, Lluís: 1 article (01/2024)
3.	Ernest, Jan: 1 article (01/2024)
4.	Kertes, Peter J: 1 article (01/2024)
5.	Kodjikian, Laurent: 1 article (01/2024)
6.	Leal, Sergio: 1 article (01/2024)
7.	Midena, Edoardo: 1 article (01/2024)
8.	Niesen, Tobias: 1 article (01/2024)
9.	Papp, András: 1 article (01/2024)
10.	Schmelter, Thomas: 1 article (01/2024)

Related Diseases

1.	Carcinoma (Carcinomatosis) 01/01/2020 - "An in vitro cytotoxicity study of iodinated Azure-A on three cell lines (HCT-116, human colon carcinoma cell line; Hep-G2, liver carcinoma cell line and HFB-4, normal human melanocytes) was carried out, and the data revealed that ioiodinated Azure A has no to very low toxic effect. " 09/24/2015 - "Methylene blue, and derivatives, azure A and azure B competitively inhibited recombinant Caspase-6 (Casp6), and inhibited Casp6 activity in transfected human colon carcinoma cells and in serum-deprived primary human neuron cultures. "
2.	Macular Degeneration (Age-Related Maculopathy) 03/01/2024 - "Intravitreal Aflibercept for Neovascular Age-Related Macular Degeneration Beyond One Year of Treatment: AZURE, a Randomized Trial of Treat-and-Extend vs. Fixed Dosing."
3.	Liver Diseases (Liver Disease) 03/01/1977 - "Ion pair extraction technique with azure A, for differentiating biles of normal subjects and patients with liver disease from patients with Crohn's disease with small bowel involvement." 03/01/1977 - "The ion pair extraction technique with Azure A solution, chloroform/methanol (equal volumes), and dilute sulfuric acid, was used to study bile-rich duodenal aspirates of (a) healthy volunteers and patients with (b) cholestatic liver disease, (c) Crohn's disease with small bowel involvement, and (d) those with primarily colon involvement. "
4.	Dehydration (Water Stress) 01/01/1977 - "When a microspectrophotometer was used to study cartilage, stained metachromatically with Azure A and Safranin O, the following 3 points were made: 1. the absorption maximum of stained cartilage matrix is identical to that reported for solutions of these dyes containing chondroitin sulfate; 2. partial enzymatic degradation of the cartilage matrix has no effect on the position of the absorption peak (although the intensity is greatly diminished); 3. ethanolic dehydration shifts the absorption peak somewhat toward the orthochromatic position, and decreases the intensity of the stain."
5.	Crohn Disease (Crohn's Disease) 03/01/1977 - "Ion pair extraction technique with azure A, for differentiating biles of normal subjects and patients with liver disease from patients with Crohn's disease with small bowel involvement." 03/01/1977 - "The ion pair extraction technique with Azure A solution, chloroform/methanol (equal volumes), and dilute sulfuric acid, was used to study bile-rich duodenal aspirates of (a) healthy volunteers and patients with (b) cholestatic liver disease, (c) Crohn's disease with small bowel involvement, and (d) those with primarily colon involvement. "

Related Drugs and Biologics

1.	Coloring Agents (Dyes)
2.	Solutions
3.	Chondroitin Sulfates (Chondroitin Sulfate)
4.	Chloroform (Trichloromethane)
5.	Methanol (Carbinol)
6.	aflibercept
7.	sulfuric acid
8.	safranine T (safranin)
9.	DNA (Deoxyribonucleic Acid)
10.	Caspase 6