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pyrromycin
Also Known As:
(1R-(1 alpha,2 beta,4 beta))-2-ethyl-1,2,3,4,6,11- hexahydro-2,5,7,10-tetrahydroxy-6,11-dioxo-4- ((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo- hexopyranosyl)oxy)-1-naphthacenecarboxylic acid, methyl ester
Networked:
4
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Polycyclic Aromatic Hydrocarbons: 2020
Naphthacenes
Anthracyclines: 9423
pyrromycin: 4
Polycyclic Compounds: 6
Polycyclic Aromatic Hydrocarbons: 2020
Naphthacenes
Anthracyclines: 9423
pyrromycin: 4
Carbohydrates: 22023
Glycosides: 2119
Aminoglycosides: 5131
Anthracyclines: 9423
pyrromycin: 4
Related Diseases
1.
Leukemia
03/01/1988 - "
The present studies revealed that pyrromycin, a closely related monosaccharide-anthracycline, induced erythroid differentiation in Friend leukemia cells and in the human leukemia cell line K 562.
"
07/01/1984 - "
The trisaccharide-containing anthracyclines aclacinomycin A (ACM) and marcellomycin (MCM) have been shown by our laboratory to be potent inducers of HL-60 leukemia cell maturation, while the monosaccharide-containing anthracyclines Adriamycin and pyrromycin were inactive and significantly less potent, respectively, as initiators of the differentiation of these malignant cells.
"
2.
Acute Erythroblastic Leukemia (Erythroleukemia)
02/01/1991 - "
The effect of adriamycin, daunomycin, N,N-dimethyladriamycin, N,N-dimethyldaunomycin, pyrromycin, marcellomycin, and aclacinomycin A on erythroid differentiation and glycoprotein synthesis in Friend erythroleukemia cells, clone F4-6 was investigated.
"
07/01/1982 - "
Effects of the structural analogues, adriamycin (ADM), daunomycin (DNM), carminomycin (CMM), 4-demethoxydaunomycin (4D-DNM), pyrromycin (PYM), marcellomycin (MCM), and aclacinomycin (ACM) upon total cell RNA synthesis and the appearance of total RNA and poly(A)+-RNA in the cytoplasm of uninduced Friend erythroleukemia cells were investigated.
"
Related Drugs and Biologics
1.
Anthracyclines
2.
Monosaccharides
3.
Doxorubicin (Adriamycin)
4.
marcellomycin
5.
Aclarubicin
6.
Daunorubicin (Cerubidine)
7.
Trisaccharides
8.
Messenger RNA (mRNA)
9.
RNA (Ribonucleic Acid)
10.
Glycoproteins (Glycoprotein)