R388 (R-factor)
drug-resistant form of enzyme, dihydrofolate reductase, biosynthesized by E coli that confers resistance to trimethoprim; increases resistance by 10,000 fold & mediates synthesis of additional dihydrofolate reductase which is 20,000x less susceptible to trimethoprim inhibition; do not confuse with Cat. G heading R FACTORS
Also Known As:
R-factor; R 388; R-388
Networked: 6
relevant articles (0 outcomes,
0 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Tateno, Toru:
2 articles
(01/2016 - 04/2014)
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2. | Jalali, Shahrzad:
1 article
(01/2016)
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3. | Monsalves, Eric:
1 article
(01/2016)
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4. | Zadeh, Gelareh:
1 article
(01/2016)
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5. | Schry, Amie R:
1 article
(05/2014)
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6. | Smith, Laura A:
1 article
(05/2014)
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7. | White, Susan W:
1 article
(05/2014)
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8. | Asa, Sylvia L:
1 article
(04/2014)
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9. | Ezzat, Shereen:
1 article
(04/2014)
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10. | Hlaing, Maw Maw:
1 article
(04/2014)
|
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